59838-64-1

Basic information

• Product Name: 2-(2-methyl)phenyl-7,8-dihydro-5(6H)-quinoline
• Synonyms: 2-(2-methyl)phenyl-7,8-dihydro-5(6H)-quinoline
• CAS NO: 59838-64-1
• Molecular Weight: 237.301
• Mol File: 59838-64-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(2-methyl)phenyl-7,8-dihydro-5(6H)-quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-methyl)phenyl-7,8-dihydro-5(6H)-quinoline(59838-64-1)
• EPA Substance Registry System: 2-(2-methyl)phenyl-7,8-dihydro-5(6H)-quinoline(59838-64-1)

Safety Data

• Hazardous Substances Data: 59838-64-1(Hazardous Substances Data)

Upstream product

• 52035-11-7 N-<(3-oxo-2-cyclohexenyl)imino>triphenylphosphorane 
• 4549-82-0 (E)-2-methylcinnamaldehyde 

Relevant articles and documents

Vinyliminophosphorane-mediated preparation of 2-arylquinoline and 4-aryl-1-azaanthraquinone derivatives. X-Ray crystal structure of 1,2-dihydro-3H-indazolo[2,3-a]quinolin-4-one

The reaction of the iminophosphorane derived from 3-azidocyclohexan-2-enone with substituted cinnamyl aldehydes affords 2-aryl-tetrahydroquinoline derivatives, which are easily converted into 2-arylquinolones. By contrast, iminophosphorane derived from 2-azidocyclohex-2-enone reacts only with α,β-unsaturated aldehydes without substituent at β-position to give 5,6-dihydro-8(7H)quinolinones. The iminophosphorane derived from 2-azido-1,4-naphthoquinone reacts with substituted cinnamyl aldehydes providing directly 4-aryl-1-azaanthraquinones. The crystal and molecular structure of 1,2-dihydro-3H-indazolo[2,3-a]quinolin-4-ono has been solved by X-Ray analysis.

Novel 5,6,7,8-tetrahydro-5-quinolines and their use as anti-inflammatory agents

Pyridine derivatives of the formula STR1 wherein R1 is an alkyl, aliphatic, a cycloalkyl, or a substituted or unsubstituted hydrocarbon aryl and the substituent is halogen, alkoxy or methylenedioxy; R2 is H or Cl; X is CN, 5-tetrazolyl, or COOH or a carboxylic acid derivative; Y is H, OH, OCOR7, NH2, NHCOR8, R9, COOH or COOR10 and R7, R8, R9 and R10 are alkyl groups of 1-10 carbon atoms; A is methylene or a carbon-to-carbon bond; and R3 and R4 are each H or alkyl groups of 1-4 carbon atoms, are useful as anti-inflammatory agents.