59870-65-4

Basic information

• Product Name: GLABROL
• Synonyms: GLABROL;(2S)-2α-(4-Hydroxy-3-prenylphenyl)-7-hydroxy-8-prenyl-2,3-dihydro-4H-1-benzopyran-4-one;[S,(-)]-2,3-Dihydro-7-hydroxy-2α-[4-hydroxy-3-(3-methyl-2-butenyl)phenyl]-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;7-Hydroxy-2α-(4-hydroxy-3-prenylphenyl)-2,3-dihydro-8-prenyl-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-[4-hydroxy-3-(methyl-2-butenyl)phenyl]-8-(3-methyl-2-butenyl)-, (2S)-;7-Hydroxy-2-[4-hydroxy-3-((E)-3-methyl-but-2-enyl)-phenyl]-8-(3-methyl-but-2-enyl)-1-benzopyran-4-one;Aids095905;Aids-095905
• CAS NO: 59870-65-4
• Molecular Formula: C₂₅H₂₈O₄
• Molecular Weight: 392.49
• Product Categories: sy
• Mol File: 59870-65-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 600°C at 760 mmHg
• Flash Point: 204.3°C
• Appearance: /
• Density: 1.166g/cm³
• Vapor Pressure: 5.41E-15mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: GLABROL(CAS DataBase Reference)
• NIST Chemistry Reference: GLABROL(59870-65-4)
• EPA Substance Registry System: GLABROL(59870-65-4)

Safety Data

• Hazardous Substances Data: 59870-65-4(Hazardous Substances Data)

Usage

Description

GLABROL, derived from the licorice root, is an extract that possesses a range of beneficial properties. It exhibits antibacterial and antiadhesive activities, along with potent antioxidative effects, making it a versatile compound with potential applications in various industries.

Uses

Used in Pharmaceutical Industry:
GLABROL is used as an active ingredient for its antibacterial and antiadhesive properties, which can help in the development of treatments for various infections and conditions related to microbial adhesion.
Used in Cosmetics Industry:
GLABROL is used as a key component in skincare products for its antioxidative effects, which can help protect the skin from oxidative stress and promote a healthier, more youthful appearance.
Used in Food Industry:
GLABROL is used as a natural preservative and additive for its antibacterial properties, which can help extend the shelf life of food products and maintain their quality.
Used in Antimicrobial Applications:
GLABROL is used as an antimicrobial agent for its ability to inhibit bacterial growth, making it a valuable tool in the development of new antimicrobial strategies and products.
Used in Antioxidant Formulations:
GLABROL is used as an antioxidant in various formulations, such as dietary supplements and nutraceuticals, to provide additional health benefits and support overall well-being.

InChI:InChI=1/C25H28O4/c1-15(2)5-7-17-13-18(8-11-21(17)26)24-14-23(28)20-10-12-22(27)19(25(20)29-24)9-6-16(3)4/h5-6,8,10-13,24,26-27H,7,9,14H2,1-4H3

Upstream product

• 69097-97-8 7,4'-dihydroxy-dihydroflavone 
• 89024-13-5 7,4'-Di(methoxymethoxy)-8,3'-di-(C-prenyl)flavanone 
• 54730-30-2 4-hydroxy-3-C-prenylbenzaldehyde 
• 19825-40-2 2,4-Dihydroxy-3-C-prenylacetophenone 
• 54730-26-6 4-methoxymethoxy-3-(3,3-dimethylallyl)-2-hydroxyacetophenone 
• 74021-58-2 4-methoxymethoxy-3-(3-methyl-but-2-enyl)-benzaldehyde 
• 89024-12-4 (E)-1-(2-hydroxy-4-(methoxymethoxy)-3-(3-methylbut-2-en-1-yl)phenyl)-3-(4-(methoxymethoxy)-3-(3-methylbut-2-en-1-yl)phenyl)prop-2-en-1-one 

Relevant articles and documents

A practical access to highly enantiomerically pure flavanones by catalytic asymmetric transfer hydrogenation

A surprisingly selective, non-enzymatic kinetic resolution of readily available, racemic β-chiral ketones enabled the title process, which was applied to a rapid synthesis of several bioactive flavanones in virtually enantiopure form (see scheme; MOM=methoxymethyl, Ts=p-toluenesulfonyl). Copyright