59935-29-4

Basic information

• Product Name: H-[15N]VAL-OH
• Synonyms: [15N]VALINE;[15N]-L-VALINE;L-VALINE-15N;H-[15N]VAL-OH;L-VALINE-15N, 99 ATOM % 15N;L-VALINE-15N 98+ ATOM % 15N ;(S)-α-Aminoisovaleric acid-15N;15N Labeled L-valine
• CAS NO: 59935-29-4
• Molecular Formula: C₅H₁₁NO₂
• Molecular Weight: 118.16
• Product Categories: Amino Acids 13C, 2H, 15N;Alphabetical Listings;Amino Acids;Amino Acids and DerivativesMass Spectrometry;Amino AcidsStable Isotopes;Biomolecular MS;Biomolecular NMR;Labeled Amino AcidsStable Isotopes;Products for SILACStable Isotopes;Proteomics Stable Isotope Labeling;Stable Isotopes;U-Z
• Mol File: 59935-29-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 295-300 °C (subl.)(lit.)
• Appearance: /
• Storage Temp.: -15°C
• CAS DataBase Reference: H-[15N]VAL-OH(CAS DataBase Reference)
• NIST Chemistry Reference: H-[15N]VAL-OH(59935-29-4)
• EPA Substance Registry System: H-[15N]VAL-OH(59935-29-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 59935-29-4(Hazardous Substances Data)

Usage

Chemical Properties

White solid

Upstream product

• 3715-29-5 sodium 3-methyl-2-oxobutyrate 

Downstream Products

• 141509-91-3 (15N)-N^α-t-Boc-L-valine 
• 1360138-53-9 ⁽¹⁵⁾N-(S)-tert-butyl (3-methyl-1-(3-methylureido)butan-2-yl)carbamate 
• 1360138-56-2 ⁽¹⁵⁾N-(S)-1-benzyl-3-(3-methyl-1-(3-methylureido)butan-2-yl)urea 

Relevant articles and documents

Stereoselective synthesis of L-[15N] amino acids with glucose dehydrogenase and galactose mutarotase as NADH regenerating system

We have developed an efficient stereospecific enzymatic synthesis of L-[15N]-valine, L-[15N]-leucine, L-[15N]- norvaline, L-[15N]-norleucine and L-[15N]-isoleucine from the corresponding α-keto acids by coupling the reactions catalysed by leucine dehydrogenase and glucose dehydrogenase/galactose mutarotase. Giving high yields of L-amino acids, the procedure is economical and easy to perform and to monitor at a synthetically useful scale (1-10 g). Copyright

Chemo-Enzymatic Syntheses of Isotopically Labelled L-Amino Acids

L-Alanine labelled with carbon-13 and nitrogen-15 has been prepared in good yield and high optical purity from achiral precursors using alanine dehydrogenase.This versatile approach may be simply adapted for the preparation of a range of isotopically labe