59981-94-1

Basic information

• Product Name: (5S,8S,9R,10S,13S,14S,17S)-9-fluoro-17-hydroxy-10,13,17-trimethyl-2,4, 5,6,7,8,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione
• Synonyms: (5S,8S,9R,10S,13S,14S,17S)-9-fluoro-17-hydroxy-10,13,17-trimethyl-2,4, 5,6,7,8,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione
• CAS NO: 59981-94-1
• Molecular Formula: C20H29FO3
• Molecular Weight: 336.4408632
• Mol File: 59981-94-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 447.1°C at 760 mmHg
• Flash Point: 224.2°C
• Appearance: /
• Density: 1.19g/cm³
• Vapor Pressure: 7.16E-10mmHg at 25°C
• Refractive Index: 1.538
• CAS DataBase Reference: (5S,8S,9R,10S,13S,14S,17S)-9-fluoro-17-hydroxy-10,13,17-trimethyl-2,4, 5,6,7,8,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (5S,8S,9R,10S,13S,14S,17S)-9-fluoro-17-hydroxy-10,13,17-trimethyl-2,4, 5,6,7,8,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione(59981-94-1)
• EPA Substance Registry System: (5S,8S,9R,10S,13S,14S,17S)-9-fluoro-17-hydroxy-10,13,17-trimethyl-2,4, 5,6,7,8,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione(59981-94-1)

Safety Data

• Hazardous Substances Data: 59981-94-1(Hazardous Substances Data)

Usage

Description

(5S,8S,9R,10S,13S,14S,17S)-9-fluoro-17-hydroxy-10,13,17-trimethyl-2,4,5,6,7,8,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione is a complex steroid hormone derivative with a cyclopenta[a]phenanthrene backbone. It features multiple functional groups, including a fluoro substituent at the 9th position and a hydroxy group at the 17th position. (5S,8S,9R,10S,13S,14S,17S)-9-fluoro-17-hydroxy-10,13,17-trimethyl-2,4, 5,6,7,8,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione is a derivative of cortisone and exhibits potent anti-inflammatory and immunosuppressive properties.

Uses

Used in Pharmaceutical Industry:
(5S,8S,9R,10S,13S,14S,17S)-9-fluoro-17-hydroxy-10,13,17-trimethyl-2,4,5,6,7,8,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione is used as a pharmaceutical agent for its potent anti-inflammatory and immunosuppressive properties. It is particularly useful in the treatment of various medical conditions that require these therapeutic effects.
Used in Research and Development:
(5S,8S,9R,10S,13S,14S,17S)-9-fluoro-17-hydroxy-10,13,17-trimethyl-2,4, 5,6,7,8,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione is also used in research and development for studying the effects of steroid hormone derivatives on biological systems. Its specific stereochemistry, denoted by the "S" and "R" designations, plays a crucial role in determining its biological activity and pharmacological profile, making it a valuable tool for understanding the structure-activity relationships of similar compounds.

InChI:InChI=1/C20H29FO3/c1-17-8-6-13(22)10-12(17)4-5-15-14-7-9-19(3,24)18(14,2)11-16(23)20(15,17)21/h12,14-15,24H,4-11H2,1-3H3/t12-,14-,15-,17-,18-,19-,20-/m0/s1

Upstream product

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Relevant articles and documents

SYNTHESIS AND TRANSFORMATIONS OF 3α-HYDROXY-5α-ANDROST-11-EN-17-ONE

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