60-91-3

Basic information

• Product Name: diethazine
• Synonyms: diethazine;PHENOTHIAZINE,10-(2-(DIETHYLAMINO)ETHYL-
• CAS NO: 60-91-3
• Molecular Formula: C₁₈H₂₂N₂S
• Molecular Weight: 298.452
• EINECS: 200-491-3
• Mol File: 60-91-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: bp4-5 195-208°; bp0.4-0.5 167-175°
• Flash Point: 209.1°C
• Appearance: /
• Density: 1.1163 (rough estimate)
• Vapor Pressure: 2.46E-07mmHg at 25°C
• Refractive Index: 1.6000 (estimate)
• PKA: pKa 9.1 (Uncertain)
• CAS DataBase Reference: diethazine(CAS DataBase Reference)
• NIST Chemistry Reference: diethazine(60-91-3)
• EPA Substance Registry System: diethazine(60-91-3)

Safety Data

• Hazardous Substances Data: 60-91-3(Hazardous Substances Data)

Usage

General Description

Diethazine is a chemical compound with the molecular formula C10H27N5O2. It is a member of the class of compounds known as triazine pesticides, which are commonly used as herbicides and fungicides. Diethazine is a broad-spectrum herbicide that is effective against a wide range of grasses and broadleaf weeds. It works by inhibiting the enzyme acetolactate synthase, which is essential for the biosynthesis of branched-chain amino acids in plants. Due to its potent activity, diethazine is used in agricultural settings to control weeds and improve crop yields. However, it is important to use diethazine with caution, as it can have negative impacts on non-target plants and organisms if not used properly.

InChI:InChI=1/C18H22N2S/c1-3-19(4-2)13-14-20-15-9-5-7-11-17(15)21-18-12-8-6-10-16(18)20/h5-12H,3-4,13-14H2,1-2H3

Upstream product

• 92-84-2 10H-phenothiazine 
• 100-35-6 2-(diethylamino)ethyl chloride 
• 21786-08-3 10-(2-chloroethyl)-10H-phenothiazine 
• 408520-43-4 N,N-diethyl-N',N'-diphenyl-ethylenediamine 
• 82-00-8 2-(N,N-diethylamino)ethyl phenothiazine carbamate 
• 18956-87-1 10H-phenothiazine-10-carbonyl chloride 
• 100-37-8 2-(Diethylamino)ethanol 

Relevant articles and documents

Phenothiazinealkaneamines for treatment of neurotoxic injury

Compounds, compositions and methods of treatment are described to control brain damage associated with anoxia or ischemia which typically follows such conditions as stroke, cardiac arrest or perinatal asphyxia. The treatment includes administration of a phenothiazinealkaneamine compound as an antagonist to inhibit excitotoxic actions at major neuronal excitatory amino acid receptor sites. Compounds of most interest are those of the formula STR1 wherein each of R1 and R2 is hydrido; wherein each of R3 and R4 is independently selected from hydrido, methyl and ethyl; wherein each of R5 and R6 is independently selected from methyl, ethyl and n-propyl; wherein X is sulfur; wherein m is zero; and wherein n is two.

Synthesis of some N-alkyl derivatives of phenothiazine

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