60048-73-9

Basic information

• Product Name: (1aR)-1aβ,3,3a,4,5,7bβ-Hexahydro-2α-hydroxy-5β-isopropenyl-3α,3aα-dimethylnaphth[1,2-b]oxiren-6(2H)-one
• Synonyms: (1aR)-1aβ,3,3a,4,5,7bβ-Hexahydro-2α-hydroxy-5β-isopropenyl-3α,3aα-dimethylnaphth[1,2-b]oxiren-6(2H)-one;Eremofortin B
• CAS NO: 60048-73-9
• Molecular Formula: C15H20O3
• Molecular Weight: 248.3175
• Mol File: 60048-73-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 376.7°C at 760 mmHg
• Flash Point: 136.8°C
• Appearance: /
• Density: 1.127g/cm³
• Vapor Pressure: 3.23E-07mmHg at 25°C
• Refractive Index: 1.526
• PKA: 14.03±0.70(Predicted)
• CAS DataBase Reference: (1aR)-1aβ,3,3a,4,5,7bβ-Hexahydro-2α-hydroxy-5β-isopropenyl-3α,3aα-dimethylnaphth[1,2-b]oxiren-6(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (1aR)-1aβ,3,3a,4,5,7bβ-Hexahydro-2α-hydroxy-5β-isopropenyl-3α,3aα-dimethylnaphth[1,2-b]oxiren-6(2H)-one(60048-73-9)
• EPA Substance Registry System: (1aR)-1aβ,3,3a,4,5,7bβ-Hexahydro-2α-hydroxy-5β-isopropenyl-3α,3aα-dimethylnaphth[1,2-b]oxiren-6(2H)-one(60048-73-9)

Safety Data

• Hazardous Substances Data: 60048-73-9(Hazardous Substances Data)

Usage

Description

(1aR)-1aβ,3,3a,4,5,7bβ-Hexahydro-2α-hydroxy-5β-isopropenyl-3α,3aα-dimethylnaphth[1,2-b]oxiren-6(2H)-one is a complex chemical compound characterized by its cyclohexene ring structure, multiple hydroxyl and methyl groups, and unique isopropenyl and oxiren functionalities. This molecule is chemically intricate and possesses potential biological activities, making it a promising candidate for various applications.

Uses

Used in Pharmaceutical Research and Drug Development:
(1aR)-1aβ,3,3a,4,5,7bβ-Hexahydro-2α-hydroxy-5β-isopropenyl-3α,3aα-dimethylnaphth[1,2-b]oxiren-6(2H)-one is utilized as a chemical entity in pharmaceutical research and drug development due to its unique structural features and potential for various biological activities.
Used in Antimicrobial Applications:
In the healthcare industry, (1aR)-1aβ,3,3a,4,5,7bβ-Hexahydro-2α-hydroxy-5β-isopropenyl-3α,3aα-dimethylnaphth[1,2-b]oxiren-6(2H)-one is used as an antimicrobial agent, leveraging its potential to combat various types of bacteria and contribute to the development of new antibiotics.
Used in Antifungal Applications:
(1aR)-1aβ,3,3a,4,5,7bβ-Hexahydro-2α-hydroxy-5β-isopropenyl-3α,3aα-dimethylnaphth[1,2-b]oxiren-6(2H)-one is also employed as an antifungal agent, harnessing its ability to inhibit fungal growth, which can be beneficial in treating fungal infections and developing antifungal medications.
Used in Antiviral Applications:
Furthermore, (1aR)-1aβ,3,3a,4,5,7bβ-Hexahydro-2α-hydroxy-5β-isopropenyl-3α,3aα-dimethylnaphth[1,2-b]oxiren-6(2H)-one is used as an antiviral agent, potentially helping to develop treatments for viral infections by targeting specific viral mechanisms.

InChI:InChI=1/C15H22O3/c1-7(2)9-6-15(4)8(3)12(17)14-13(18-14)10(15)5-11(9)16/h8-10,12-14,17H,1,5-6H2,2-4H3

Upstream product

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• 79801-46-0 Acetic acid (1R,2S,4R,8aR)-4-bromo-1,8a-dimethyl-6-oxo-1,2,3,4,6,7,8,8a-octahydro-naphthalen-2-yl ester 
• 38655-97-9 5β,6β-Dimethyl-2-oxo-7β-hydroxy-Δ¹-octalin 
• 79801-49-3 (3S,4aR,5R,6S)-6-Hydroxy-3-(1-hydroxy-1-methyl-ethyl)-4a,5-dimethyl-4,4a,5,6-tetrahydro-3H-naphthalen-2-one 
• 69369-66-0 5β,6β-Dimethyl-2-oxo-7β-acetoxy-Δ¹-octalin 
• 79801-48-2 Acetic acid (1R,2S,8aR)-1,8a-dimethyl-6-oxo-1,2,6,7,8,8a-hexahydro-naphthalen-2-yl ester 
• 79802-88-3 (4aR,5R,6S)-6-Hydroxy-4a,5-dimethyl-4,4a,5,6-tetrahydro-3H-naphthalen-2-one 
• 55050-26-5 5β,6β-dimethyl-2,7-dioxo-Δ^(1(10))-octalin 
• 79801-50-6 (1aR,2R,3R,3aR,5S,7bS)-2-Hydroxy-5-(1-hydroxy-1-methyl-ethyl)-3,3a-dimethyl-1a,3,3a,4,5,7b-hexahydro-2H-1-oxa-cyclopropa[a]naphthalen-6-one 

Relevant articles and documents

STEREOSELECTIVE TOTAL SYNTHESIS OF (+/-)-EREMOFORTIN B, A SESQUITERPENOID MYCOTOXIN OF Penicillium roqueforti

The stereoselective total synthesis of (+/-)-eremofortin B (1), a sesquiterpenoid mycotoxin of Penicillium roqueforti, from 5β,6β-dimethyl-2,7-dioxo-Δ1(10)-octalin (2) is described.Stereochemistry of eremofortin B was confirmed as shown in 1.