600727-37-5

Basic information

• Product Name: 1-{1-[3-(4-chlorophenyl)-prop-2-ynyl]-1H-indol-2-yl}ethanone
• Synonyms: 1-{1-[3-(4-chlorophenyl)-prop-2-ynyl]-1H-indol-2-yl}ethanone
• CAS NO: 600727-37-5
• Molecular Weight: 307.779
• Mol File: 600727-37-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-{1-[3-(4-chlorophenyl)-prop-2-ynyl]-1H-indol-2-yl}ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{1-[3-(4-chlorophenyl)-prop-2-ynyl]-1H-indol-2-yl}ethanone(600727-37-5)
• EPA Substance Registry System: 1-{1-[3-(4-chlorophenyl)-prop-2-ynyl]-1H-indol-2-yl}ethanone(600727-37-5)

Safety Data

• Hazardous Substances Data: 600727-37-5(Hazardous Substances Data)

Upstream product

• 637-87-6 1-Chloro-4-iodobenzene 
• 600727-36-4 1-(1-prop-2-ynyl-1H-indol-2-yl)ethanone 
• 4264-35-1 2-acetylindole 

Downstream Products

• 1173768-36-9 7-(4-chlorobenzyl)-9-(morpholin-1-yl)pyrido[1,2-a]indole 
• 1173768-28-9 7-(4-chlorobenzyl)-9-(pyrrolidin-1-yl)pyrido[1,2-a]indole 

Relevant articles and documents

Novel intramolecular cyclization of N-alkynyl heterocycles containing proximate nucleophiles

Intramolecular cyclization of 2-acyl-1-propargyl-1H-indoles in the presence of ammonia provides an easy entry to pyrazino[1,2-a]indole nucleus.

Intramolecular cyclization of δ-iminoacetylenes: A new entry to pyrazino[1,2-a]indoles

The synthesis of the pyrazino[1,2-a]indole nucleus was achieved by intramolecular cyclization of several 2-carbonyl-1-propargylindoles in the presence of ammonia. The reaction conditions were optimized using microwave heating and a pool of catalysts. Cycl