60075-04-9

Basic information

• Product Name: 2-(4-Hydroxyphenoxy)propionic acid methyl ester
• Synonyms: 2-(4-HYDROXY-PHENOXY)PROPIONIC ACID METHYL ESTER;UUYSCNGPNOYZMC-UHFFFAOYSA-N
• CAS NO: 60075-04-9
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.2
• Mol File: 60075-04-9.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 313.4°C at 760 mmHg
• Flash Point: 121.6°C
• Appearance: /
• Density: 1.187g/cm³
• Vapor Pressure: 0.000271mmHg at 25°C
• Refractive Index: 1.522
• CAS DataBase Reference: 2-(4-Hydroxyphenoxy)propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Hydroxyphenoxy)propionic acid methyl ester(60075-04-9)
• EPA Substance Registry System: 2-(4-Hydroxyphenoxy)propionic acid methyl ester(60075-04-9)

Safety Data

• Hazardous Substances Data: 60075-04-9(Hazardous Substances Data)

Usage

Description

2-(4-Hydroxyphenoxy)propionic acid methyl ester, also known as Methyl 2-(4-Hydroxyphenoxy)propionate, is an organic compound that serves as a crucial intermediate in the synthesis of various chemical compounds. It is characterized by the presence of a hydroxyphenoxy group attached to a propionic acid chain, with a methyl ester functional group.

Uses

Used in Agrochemical Industry:
2-(4-Hydroxyphenoxy)propionic acid methyl ester is used as an intermediate in the synthesis of (±)-Fluazifop (F407430), a grass-selective herbicide. This herbicide is effective in inhibiting acetyl-CoA carboxylase in sensitive plant species, thereby controlling grass growth and offering selective weed control for agricultural applications.

InChI:InChI=1/C10H12O4/c1-7(10(12)13-2)14-9-5-3-8(11)4-6-9/h3-7,11H,1-2H3

Upstream product

• 59058-36-5 methyl 4-(benzyloxy)-α-phenoxypropionate 
• 103-16-2 4-Benzyloxyphenol 
• 67-56-1 methanol 
• 94050-90-5 (RS)-2-(4-hydroxyphenoxy)propionic acid 
• 5445-17-0 Methyl 2-bromopropionate 
• 96562-50-4 methyl 2-(4-(1-methylethenyl)phenoxy)propanoate 
• 7664-93-9 sulfuric acid 
• 96562-61-7 2-(4-(1-methylethenyl)phenoxy)propanoic acid 
• 77-76-9 2,2-dimethoxy-propane 
• 123-31-9 hydroquinone 
• 17639-93-9 2-chloro-propionic acid methyl ester 
• 2065-24-9 methyl 2-phenoxypropanoate 
• 91497-60-8 methyl 2-(4-acetylphenoxy)propionate 
• 108-95-2 phenol 

Downstream Products

• 113411-73-7 Methyl 2<4-(4-amino-5-cyanopyrimidyl-2-oxy)phenoxy>propionate 
• 347162-38-3 2-[4-(7-nitro-quinoxalin-2-yloxy)-phenoxy]-propionic acid methyl ester 
• 347162-29-2 2-[4-(8-chloro-quinoxalin-2-yloxy)-phenoxy]-propionic acid methyl ester 
• 347162-27-0 2-[4-(5-chloro-quinoxalin-2-yloxy)-phenoxy]-propionic acid methyl ester 
• 347162-35-0 2-[4-(7-iodo-quinoxalin-2-yloxy)-phenoxy]-propionic acid methyl ester 
• 347162-40-7 2-[4-(7-azido-quinoxalin-2-yloxy)-phenoxy]-propionic acid methyl ester 
• 347162-44-1 2-[4-(8-chloro-7-methoxy-quinoxalin-2-yloxy)-phenoxy]-propionic acid methyl ester 
• 347162-42-9 2-[4-(7-chloro-8-methoxy-quinoxalin-2-yloxy)-phenoxy]-propionic acid methyl ester 
• 66546-20-1 4-(6-chlorobenzoxazolyloxy)phenoxypropionic acid methyl ester 
• 66441-10-9 methyl 2-{4-[(6-chloro-2-benzothiazolyl)oxy]phenoxy}propionate 
• 66441-22-3 2-[4-(5-chloro-benzooxazol-2-yloxy)-phenoxy]-propionic acid methyl ester 
• 84991-07-1 methyl 2-{4-[(1-oxide-1,2,4-benzotriazin-3-yl)oxy]phenoxy}propionate 
• 445041-38-3 methyl 2-{4-[(6-chloro-1-oxide-1,2,4-benzotriazin-3-yl)oxy]phenoxy}propionate 

Relevant articles and documents

Synthetic method 4 - alkoxyphenol compounds

The invention discloses a synthetic method of 4 - alkoxyphenol compounds, and belongs to the field of organic chemical synthesis. The method is as follows: An aryl alkyl ether compound is added to the sealing tube. The catalyst dimerization acetic acid rhodium and the oxidizing agent iodobenzene diethyl ester are added, a solvent trifluoroacetic anhydride is added, and the 4 -alkoxyphenol compound is prepared by heating reaction. To the invention, high regioselectivity direct hydroxylation of the aryl alkyl ether compound is realized, the application range of the substrate is wide, the yield is high, the activity after amplification reaction does not significantly decay, and higher yield is still obtained. The utility model has good practicability and industrial application prospect.

Method for synthesizing herbicide clodinafop-propargyl key intermediate

The invention discloses a method for synthesizing a herbicide clodinafop-propargyl key intermediate. According to the method, methyl 2-chloropropionate and hydroquinone are used as starting raw materials, under the catalytic action of inorganic alkali, nucleophilic substitution reaction is conducted, and methyl (R,S)-2-(4-hydroxyphenoxy)propionate is obtained; the generated methyl (R,S)-2-(4-hydroxyphenoxy)propionate is subjected to resolution hydrolysis reaction under the action of aspergillus oryzae WZ007, and a methyl (R)-(+)-2-(4-hydroxyphenoxy)propionate product is obtained; the generatedproduct is subjected to hydrolysis reaction continuously to obtain a target product R(+)-2-(4-hydroxyphenoxy)propionic acid. The synthesis method is simple; in the synthesis process, thalli of the aspergillus oryzae WZ007 are used for catalyzing selective hydrolysis of a methyl (R,S)-2-(4-hydroxyphenoxy)propionate substrate, thus the R-configuration ester and the S-configuration acid are obtained, the purpose of resolution is achieved, moreover, the raw materials of the method are cheap, the production cost is low, and the economic performance is good, so that the method has good applicationprospects.

6-chlorobenzoxazol-oxyphenoxy propionate compound and application thereof

The invention belongs to the field of herbicides and particularly relates to a 6-chlorobenzoxazol-oxyphenoxy propionate compound and application thereof. The compound is shown in a general formula (I). The compound provided by the invention not only has e