60076-09-7

Basic information

• Product Name: m-Iodobenzylchloride
• Synonyms: m-Iodobenzylchloride;3-iodobenzylchloride;1-(ChloroMethyl)-3-iodobenzene
• CAS NO: 60076-09-7
• Molecular Formula: C₇H₆ClI
• Molecular Weight: 252.48
• Mol File: 60076-09-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: m-Iodobenzylchloride(CAS DataBase Reference)
• NIST Chemistry Reference: m-Iodobenzylchloride(60076-09-7)
• EPA Substance Registry System: m-Iodobenzylchloride(60076-09-7)

Safety Data

• Hazardous Substances Data: 60076-09-7(Hazardous Substances Data)

Usage

General Description

m-Iodobenzylchloride is a chemical compound with the molecular formula C7H6ClI and a molecular weight of 234.48 g/mol. It is a colorless to pale yellow liquid with a strong odor, and it is primarily used as a building block in organic synthesis and pharmaceutical research. m-Iodobenzylchloride is commonly employed in the preparation of various pharmaceuticals, as well as in the synthesis of biologically active molecules and agrochemicals. It is also used as a reagent in the production of organic and inorganic compounds, and as an intermediate in the manufacturing of specialty chemicals. Additionally, m-Iodobenzylchloride is considered to be potentially harmful if inhaled, ingested, or comes into contact with the skin, and appropriate safety precautions should be observed when handling this chemical.

Upstream product

• 57455-06-8 3-iodobenzylalcohol 
• 10026-13-8 phosphorus pentachloride 

Downstream Products

• 130504-76-6 m-iodobenzyl cholesteryl ether 
• 474010-13-4 dimethyl (3-iodobenzyl)malonate 

Relevant articles and documents

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THIAZOLE AND OXAZOLE KINASE INHIBITORS

The present invention is concerned with substituted azole derivatives that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant proteine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. In particular, several of these compounds are potent and selective Flt-3 inhibitors or/and syk inhibitors.

Amines useful as brain imaging agents

Certain radioiodine containing amines useful as brain imaging agents are disclosed. The compounds of the invention are represented by the formula STR1 wherein I is a radioisotope of iodine with I-123 being preferred, R is lower alkyl or halogen, R1 and R2 are the same or different and are selected from the group consisting of hydrogen and lower alkyl, R3 and R4 are the same or different and are selected from the group consisting of hydrogen, alkyl, aryl, substituted aryl, aralkyl, substituted aralkyl and substituted carbamoyl methyl or R3 and R4 taken together with the nitrogen to which they are attached form a 5- or 6-membered ring which may be substituted with one or more lower alkyl groups, x is 0 to 4, y is 0 to 3 and z is 0 or 1 and pharmaceutically acceptable acid addition salts thereof.