60122-72-7

Basic information

• Product Name: BETA-TBU-DL-ALANINE
• Synonyms: 2-AMINO-4,4-DIMETHYL-PENTANOIC ACID;DL-T-BUTYLALANINE;DL-NEOPENTYLGLYCINE;DL-GAMMA-METHYLLEUCINE;H-BETA-TBU-DL-ALA-OH;H-DL-ALA(TBU)-OH;H-DL-BETA-TBU-ALA-OH;H-DL-LEU(ME)-OH
• CAS NO: 60122-72-7
• Molecular Formula: C₇H₁₅NO₂
• Molecular Weight: 145.2
• Mol File: 60122-72-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 272-274 °C (dec.)
• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: BETA-TBU-DL-ALANINE(CAS DataBase Reference)
• NIST Chemistry Reference: BETA-TBU-DL-ALANINE(60122-72-7)
• EPA Substance Registry System: BETA-TBU-DL-ALANINE(60122-72-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 60122-72-7(Hazardous Substances Data)

Usage

General Description

BETA-TBU-DL-ALANINE is a chemical compound that belongs to the class of α-amino acids. It is a derivative of the natural amino acid alanine, in which a tert-butyl group is attached to the beta carbon. This modification enhances the chemical stability and lipophilicity of the molecule, making it suitable for pharmaceutical and biochemical applications. BETA-TBU-DL-ALANINE has been studied for its potential use as a building block in the synthesis of peptide-based drugs and as a chiral auxiliary in asymmetric synthesis. It is also used in the production of specialty chemicals and as a research tool in the development of new pharmaceuticals. Overall, BETA-TBU-DL-ALANINE is a versatile compound with diverse applications in the fields of chemistry, biochemistry, and medicine.

Upstream product

• 57224-49-4 (Z)-2-Formylamino-4,4-dimethyl-pent-2-enoic acid ethyl ester 
• 479353-90-7 2-amino-4,4-dimethyl-pentanenitrile 
• 88319-39-5 2-carbamoyl-4,4-dimethylpentanoic acid 
• 39168-28-0 (E)-2-cyano-4,4-dimethyl-pent-2-enoic acid 
• 2987-16-8 3,3-dimethylbutyrylaldehyde 
• 7065-46-5 3,3-dimethylbutanoic acid chloride 
• 88319-38-4 2-cyano-4,4-dimethylpentanoic acid 
• 34906-87-1 4,4-dimethyl-2-oxo-pentanoic acid 
• 88319-40-8 N-formyl-D-neopentylglycine 
• 88319-40-8 N-formyl-L-neopentylglycine 

Downstream Products

• 88319-46-4 N-2-nitrobenzenesulfenyl-L-neopentylglycine 
• 88319-44-2 N-benzoyloxycarbonyl-L-neopentylglycine 
• 112674-65-4 acetyl-L-neopentylglycine 
• 57224-50-7 D-neopentylglycine 
• 57224-50-7 L-neopentylglycine 
• 79777-82-5 N-tert-butyloxycarbonyl-D-neopentylglycine 
• 79777-82-5 N-tert-butyloxycarbonyl-L-neopentylglycine 
• 459836-80-7 C₁₄H₁₉NO₃ 
• 65302-98-9 2-hydroxy-4,4-dimethylpentanoic acid 
• 199170-91-7 N-acetyl-γ-methyl-d,l-leucine 

Relevant articles and documents

DL-neopentyl glycine intermediate and preparation method thereof and preparation method of derivative based on intermediate

The invention relates to the field of amino acid preparation, in particular to a DL-neopentyl glycine intermediate and a preparation method thereof and a preparation method of a derivative based on the intermediate. The preparation method of the DL-neopentyl glycine intermediate comprises an acetylation reaction, a condensation reaction, a hydrolysis reaction, an oximation reaction and a reductionreaction, and then a corresponding derivative is obtained through the acetylation reaction and resolution. According to the preparation method, the reaction time is shortened, the reaction is more thorough and the DL-neopentyl glycine can be obtained; two methods for preparing the derivative D-neopentyl glycine and the derivative L-neopentyl glycine are obtained at the same time, the prepared product is high in purity, secondary refining is not needed, the production cost is reduced, and industrial large-scale production is facilitated.

Synthesis of L α amino acids structurally related to isoleucine

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