60124-17-6 Usage
General Description
Withaferin-A is a naturally occurring steroid lactone found in the plant Withania somnifera, commonly known as Ashwagandha. It has been identified as a potential anti-inflammatory, anti-tumor, and immunomodulatory agent. Withastramonolide, 12-deoxy-(sh) is a derivative of withaferin-A, which has shown promising anticancer properties in preclinical studies. It exhibits cytotoxic activity against various cancer cell lines and has the potential to be developed into a novel therapeutic agent for the treatment of cancer. Additionally, it has also demonstrated anti-inflammatory and neuroprotective effects, making it a versatile compound with potential applications in various disease conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 60124-17-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,1,2 and 4 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 60124-17:
(7*6)+(6*0)+(5*1)+(4*2)+(3*4)+(2*1)+(1*7)=76
76 % 10 = 6
So 60124-17-6 is a valid CAS Registry Number.
60124-17-6Relevant articles and documents
Baimantuoluosides A-C, three new withanolide glucosides from the flower of Datura metel L.
Kuang, Haixue,Yang, Bingyou,Tang, Ling,Xia, Yonggang,Dou, Deqiang
experimental part, p. 1315 - 1323 (2009/10/17)
In search for bioactive compounds from the flower of Datura metel L., three new withanolide glucosides, namely baimantuoluosides A, B, and C (1-3, resp.) were isolated. Enzymatic hydrolysis of 1-3 afforded the corresponding aglycones 1a, 2a, and 3a, respectively. The structures of the new compounds were elucidated as (5α,6α,7α,12β,22R)-5,12-dihydroxy-1,26- dioxo-6,7:22,26-diepoxyergosta-2,24-dien-27-yl β-D-glucopyranoside (1), (5α,6α,7α,12α,22R)-5,12-dihydroxy-1,26-dioxo-6,7:22, 26-diepoxyergosta-2,24-dien-27-yl β-D-glucopyranoside (2), (5α,6α,7α,22R)-5-hydroxy-1,26-dioxo-6,7:22, 26-diepoxyergosta-2,24-dien-27-yl β-D-glucopyranoside (3) on the basis of chemical and physicochemical evidence, and are further confirmed by the structure determination by X-ray diffraction of withanolide aglycone 1a.
