6013-92-9Relevant articles and documents
Hydrogen-bonded networks in 1-(4-methoxyphenyl)-2,2-dimethyl-propan-1-ol
Glinski, Marek,Wilczkowska, Ewa,Madura, Izabela D.,Zachara, Janusz
, p. o720-o722 (2007)
The asymmetric unit of the title compound, C12H18O2, contains two independent mol-ecules. They differ only slightly in conformation but form completely different inter-molecular hydrogen-bonded arrays. One molecule exhibits disorder in the hydroxy group r
Arylboronic Acid Catalyzed C-Alkylation and Allylation Reactions Using Benzylic Alcohols
Estopi?á-Durán, Susana,McLean, Euan B.,Donnelly, Liam J.,Hockin, Bryony M.,Taylor, James E.
supporting information, p. 7547 - 7551 (2020/10/09)
The arylboronic acid catalyzed dehydrative C-alkylation of 1,3-diketones and 1,3-ketoesters using secondary benzylic alcohols as the electrophile is reported, forming new C-C bonds (19 examples, up to 98% yield) with the release of water as the only byproduct. The process is also applicable to the allylation of benzylic alcohols using allyltrimethylsilane as the nucleophile (12 examples, up to 96% yield).
Forming tertiary organolithiums and organocuprates from nitrile precursors and their bimolecular reactions with carbon electrophiles to form quaternary carbon stereocenters
Schnermann, Martin J.,Untiedt, Nicholas L.,Jiménez-Osés, Gonzalo,Houk, Kendall N.,Overman, Larry E.
supporting information, p. 9581 - 9586 (2012/11/14)
Unstabilized tertiary organolithium intermediates are conveniently generated by reductive decyanation of nitriles, and these reagents and their derived cuprates couple in useful yields with carbon- centered electrophiles (see example). Chiral tertiary org