601481-95-2

Basic information

• Product Name: Benzenesulfonamide, N-[2-(hydroxymethyl)phenyl]-4-methoxy-
• CAS NO: 601481-95-2
• Molecular Formula: C14H15NO4S
• Molecular Weight: 293.343
• Mol File: 601481-95-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, N-[2-(hydroxymethyl)phenyl]-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-[2-(hydroxymethyl)phenyl]-4-methoxy-(601481-95-2)
• EPA Substance Registry System: Benzenesulfonamide, N-[2-(hydroxymethyl)phenyl]-4-methoxy-(601481-95-2)

Safety Data

• Hazardous Substances Data: 601481-95-2(Hazardous Substances Data)

Upstream product

• 118-92-3 anthranilic acid 
• 5344-90-1 2-Aminobenzyl alcohol 
• 98-68-0 4-methoxy-phenyl-sulphonyl chloride 

Relevant articles and documents

Ynamide Smiles Rearrangement Triggered by Visible-Light-Mediated Regioselective Ketyl-Ynamide Coupling: Rapid Access to Functionalized Indoles and Isoquinolines

In the past decades, significant advances have been made on radical Smiles rearrangement. However, the eventually formed radical intermediates in these reactions are limited to the amidyl radical, except for the few examples initiated by a N-centered radical. Here, a novel and practical radical Smiles rearrangement triggered by photoredox-catalyzed regioselective ketyl-ynamide coupling is reported, which represents the first radical Smiles rearrangement of ynamides. This method enables facile access to a variety of valuable 2-benzhydrylindoles with broad substrate scope in generally good yields under mild reaction conditions. In addition, this chemistry can also be extended to the divergent synthesis of versatile 3-benzhydrylisoquinolines through a similar ketyl-ynamide coupling and radical Smiles rearrangement, followed by dehydrogenative oxidation. Moreover, such an ynamide Smiles rearrangement initiated by intermolecular photoredox catalysis via addition of external radical sources is also achieved. By control experiments, the reaction was shown to proceed via key ketyl radical and α-imino carbon radical intermediates.

Structure-activity relationship of the cinnamamide family of antibiotic potentiators for methicillin-resistant: Staphylococcus aureus (MRSA)

Methicillin-resistant Staphylococcus aureus (MRSA) is a global public health threat. MRSA has evolved a complex set of biochemical processes that mobilize the organism for inducible resistance on challenge by β-lactam antibiotics. Interfering pharmacologi

Synthesis of novel nitrogen-containing ligands for the enantioselective addition of diethylzinc to aldehydes

New nitrogen-containing ligands derived from the (1R,2R)-trans-cyclohexanediamine chiral core unit have been synthesized and fully characterized. Their catalytic activity was tested in the asymmetric addition of diethylzinc to aldehydes leading to the res