602-04-0

Basic information

• Product Name: 3-[bis(2-methyl-1H-indol-3-yl)methyl]-2-methyl-1H-indole
• Synonyms: 3-[bis(2-methyl-1H-indol-3-yl)methyl]-2-methyl-1H-indole
• CAS NO: 602-04-0
• Molecular Formula: C28H25N3
• Molecular Weight: 403.5182
• Mol File: 602-04-0.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 675.7°Cat760mmHg
• Flash Point: 297.9°C
• Appearance: /
• Density: 1.265g/cm³
• CAS DataBase Reference: 3-[bis(2-methyl-1H-indol-3-yl)methyl]-2-methyl-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[bis(2-methyl-1H-indol-3-yl)methyl]-2-methyl-1H-indole(602-04-0)
• EPA Substance Registry System: 3-[bis(2-methyl-1H-indol-3-yl)methyl]-2-methyl-1H-indole(602-04-0)

Safety Data

• Hazardous Substances Data: 602-04-0(Hazardous Substances Data)

Upstream product

• 95-20-5 2-methyl-1H-indole 
• 64-18-6 formic acid 
• 5416-80-8 2-methyl-1H-indole-3-carbaldehyde 
• 64-17-5 ethanol 
• 525-58-6 3-[3H-indol-3-ylidenemethyl]-1H-indole 
• 19693-75-5 2-methoxy-1,3-dioxolane 
• 6267-24-9 tris(ethylsulfanyl)methane 
• 59959-16-9 3,3'-vinylidenebis(2-methylindole) 
• 122-51-0 orthoformic acid triethyl ester 
• 57397-70-3 ethyl 3-(ethoxymethylene)-2,4-dioxovalerate 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 35824-98-7 1,3-dimethyl-5-[(dimethylamino)methylidene]pyrimidine-2,4,6(1H,3H,5H)-trione 
• 4316-93-2 4,6-dichloro-5-nitropyrimidine 
• 611-35-8 4-chloroquinoline 

Relevant articles and documents

Transformations of 6,7-difluoroquinoxaline with Indoles: Synthesis of Indole-Substituted 6,7-difluoroquinoxalines and Tris(indol-3-yl)methane Derivatives

6,7-Difluoroquinoxaline (1) reacted with 1- and 2-methylindoles (2a and 2b) with heating in AcOH to give products from substitution of H in the heterocyclic fragment (3a and 3b) and tris(indol-3-yl)methane derivatives (4a and 4b).

Efficient and convenient method for the synthesis of symmetrical triindolylmethanes catalyzed by iodine

Indoles reacted with triethyl orthoformate in the presence of a catalytic amount of iodine at room temperature to give the corresponding symmetrical triindolylmethanes (TIMs) in good to high yields. Copyright Taylor & Francis Group, LLC.

C-C bond cleavage: Metal-free-catalyzed reaction of Betti bases with various heterocycles under microwave irradiation

The reaction of Betti bases with various heterocycles in the presence of p-toluenesulphonic acid (PTSA) under microwave irradiation gives bis(heterocycle)methanes through benzyl transfer. The reaction proceeds via the cleavage of C-N bond followed by C-C

Eco-friendly synthesis of condensed nitrogen heterocycles: A brief experience from our group

In order to develop eco-friendly syntheses of condensed nitrogen heterocycles, solvent-free syntheses on solid acidic catalysts and aqueous reactions using a phase transfer catalyst (PTC) were successfully carried out. The catalysts used were (i) TLC-grade silica gel G (SiO2), (ii) SiO2 doped with 10 mol% phosphoric acid (H3PO 4-SiO2), (iii) Montmorillonite K10 clay (K10), (iv) acid-washed K10 clay (acid-clay), (v) K10 doped with one equivalent (with respect to substrate) of tosic acid (TsOH-K10) and (vi) cetylpyridinium bromide (CPB) (5 mol%) as the PTC. The reactions were carried out at room temperature (rt), at 60-70°C (oven) or under microwave irradiation (MWI).