6020-61-7 Usage
Description
(2E)-3-(4-fluorophenyl)-1-(3-methoxyphenyl)prop-2-en-1-one is an organic compound with the molecular formula C17H13FO2. It is a ketone that features a 4-fluorophenyl group and a 3-methoxyphenyl group attached to a prop-2-en-1-one backbone. (2E)-3-(4-fluorophenyl)-1-(3-methoxyphenyl)prop-2-en-1-one is recognized for its structural features that make it a valuable intermediate in the synthesis of pharmaceuticals and biologically active molecules.
Uses
Used in Organic Synthesis:
(2E)-3-(4-fluorophenyl)-1-(3-methoxyphenyl)prop-2-en-1-one is used as a building block in organic synthesis for the creation of various pharmaceuticals and biologically active molecules. Its unique structural elements contribute to the development of complex organic compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (2E)-3-(4-fluorophenyl)-1-(3-methoxyphenyl)prop-2-en-1-one serves as an important intermediate. It aids in the production of drugs and other bioactive compounds, thanks to its distinctive properties that are beneficial for medicinal applications.
Used in Pharmaceutical Sciences:
(2E)-3-(4-fluorophenyl)-1-(3-methoxyphenyl)prop-2-en-1-one is utilized as a useful tool in pharmaceutical sciences. Researchers leverage its unique properties to advance their work, making it an essential component in the discovery and development of new drugs and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 6020-61-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,0,2 and 0 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6020-61:
(6*6)+(5*0)+(4*2)+(3*0)+(2*6)+(1*1)=57
57 % 10 = 7
So 6020-61-7 is a valid CAS Registry Number.
6020-61-7Relevant articles and documents
Synthesis and biological activity evaluation of novel peroxo-bridged derivatives as potential anti-hepatitis B virus agents
Jia, Menglu,Zhao, Rui,Xu, Bing,Yan, Wenqiang,Chu, Fuhao,Gu, Hongshun,Xie, Tianxin,Xiang, Hongjun,Ren, Jian,Chen, Dagang,Wang, Penglong,Lei, Haimin
, p. 148 - 151 (2017/02/05)
Previous studies have demonstrated that natural steroid compounds containing a peroxide bridge exhibited potential anti-hepatitis B virus activity. To continue our research, a simple and regioselective methodology, using Eosin Y as a clean photosensitized oxidation catalyst, was developed for the synthesis of a peroxide bridge in steroids. The method that using Eosin Y as the catalyst was exposed to visible light and furbished in high yields, did not involve tedious work-up or purification, and avoided using environmentally hazardous solvents. It can be regarded as a green protocol. Moreover, a series of cholesterol and β-sitosterol derivatives containing a peroxide bridge were synthesized using this method and screened for their anti-HBV activity. Among the compounds synthesized in this research, 5α,8α-cyclicobioxygen-6-vinyl-3-oxo-cholesterone (1f, 3.13 μg ml?1) had the most potent activity with inhibition rates of 77.45% ± 6.01% and 58.73% ± 8.64% on the secretion of HBsAg and HBeAg antigens, respectively, after 8 days. Further acute toxicity test showed that the LD50 value of compound 1f was 362.46 mg kg?1 after an intraperitoneal injection in mice. Moreover, structure-activity relationships of cholesterol and β-sitosterol derivatives were briefly discussed.
Steroids from sponges
Sheikh,Djerassi
, p. 4095 - 4103 (2007/10/10)
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