60208-05-1 Usage
Description
2-bromo-1-(3-bromo-4-methyl-phenyl)-ethanone is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its bromine-substituted aromatic ring and ethanone functional group, which contribute to its reactivity and utility in chemical reactions.
Uses
Used in Pharmaceutical Synthesis:
2-bromo-1-(3-bromo-4-methyl-phenyl)-ethanone is used as an intermediate in the synthesis of 3-Bromo Zolpidem (B809563). 2-bromo-1-(3-bromo-4-methyl-phenyl)-ethanone is an impurity of Zolpidem (Z650000), which is a selective non-benzodiazepine GABAA receptor agonist. Zolpidem is widely used for its sedative and hypnotic effects, helping to treat insomnia and other sleep disorders.
Used in the Chemical Industry:
In the chemical industry, 2-bromo-1-(3-bromo-4-methyl-phenyl)-ethanone may be utilized as a building block for the development of other organic compounds with potential applications in various fields, such as materials science, agrochemicals, and pharmaceuticals. Its unique structural features make it a valuable component in the synthesis of complex molecules with specific properties and functions.
Check Digit Verification of cas no
The CAS Registry Mumber 60208-05-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,2,0 and 8 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 60208-05:
(7*6)+(6*0)+(5*2)+(4*0)+(3*8)+(2*0)+(1*5)=81
81 % 10 = 1
So 60208-05-1 is a valid CAS Registry Number.
60208-05-1Relevant articles and documents
SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES
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Page/Page column 241-242, (2020/01/10)
The invention relates to substituted dihydropyrazolo pyrazine carboxamide derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and diabetes, and also urogenital and ophthalmic disorders.
1,3-Dibromo-5,5-dimethylhydantoin mediated oxidative amidation of terminal alkenes in water
Ma, Chunhua,Fan, Guojie,Wu, Ping,Li, Zhi,Zhou, Yang,Ding, Qingjie,Zhang, Wei
, p. 9889 - 9894 (2017/12/12)
A variety of terminal alkenes were converted to the corresponding amides in yields of 25 to 86% in water via treatment with 1,3-dibromo-5,5-dimethylhydantoin, followed by reaction with molecular iodine and aq. NH3 (or amine) in one pot. This metal- and organic solvent-free protocol is not only suitable for styrene derivatives, but also, for the first time, works well on terminal aliphatic alkenes.
2-ACYLAMINOTHIAZOLES FOR THE TREATMENT OF CANCER
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Page/Page column 74, (2015/01/16)
The present invention relates to inhibitors of the oncogenic protein kinase ALK of formula (I) as herein described and pharmaceutical compositions thereof. The compounds of formula (I) are useful in the preparation of a medicament, in particular for the treatment of cancer.
