602275-62-7Relevant articles and documents
A new asymmetric synthesis of 2,6-cis-disubstituted 4-methylenepiperidines: Total synthesis of (+)-alkaloid 241D and (+)-isosolenopsin A
Monfray, Jeremy,Gelas-Mialhe, Yvonne,Gramain, Jean-Claude,Remuson, Roland
, p. 1025 - 1034 (2005)
A highly diastereoselective synthesis of 2,6-cis-disubstituted-4- methylenepiperidines based on a Mannich type intramolecular cyclization of an allylsilane on an iminium ion is described. The synthetic potential of this methodology is demonstrated by the
BENZIMIDAZOLONE CHYMASE INHIBITORS
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Page/Page column 186, (2009/01/20)
Disclosed are small molecule inhibitors which are useful in treating various diseases and conditions involving chymase.