60234-78-8Relevant articles and documents
COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS
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Page/Page column 728, (2015/02/02)
The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.
Platinum- and gold-catalyzed hydroalkoxylation and tetramerization of propiolate esters
Chen, Qian,Zhang, Changyuan,Wen, Chunxiao,Fang, Jin,Du, Zhiyun,Wu, Dongling
, p. 101 - 105 (2014/08/18)
PtCl2 was found to efficiently catalyze intermolecular additions of propiolate esters with alcohols. The reaction of propiolate esters and alcohols in the presence of PtCl2 gave (E)-vinyl ethers as the major products at 60 °C, whereas alkyl 3,3-dialkoxypropanoates were predominantly obtained when the reaction temperature was set to 80°C. On the other hand, a novel regioselective tetramerization of propiolate esters catalyzed by AuCl3 under mild conditions afforded 1,2,5,6-tetrasubstituted- cyclooctatetraene (1,2,5,6-COT) in moderate yields.