6030-18-8 Usage
Description
(E)-N-hydroxy-1-(5-nitrothiophen-2-yl)methanimine is a chemical compound that belongs to the class of organic compounds known as nitrothiophenes. It is characterized by a nitro group attached to a thiophene ring, as well as an N-hydroxyimine functional group. (E)-N-hydroxy-1-(5-nitrothiophen-2-yl)methanimine has potential applications in synthetic chemistry and pharmaceutical research, as it may serve as a precursor to various organic molecules. Additionally, it may exhibit biological activity and therefore be of interest in drug discovery and development. Further studies are needed to fully understand the properties and potential uses of this chemical.
Uses
Used in Synthetic Chemistry:
(E)-N-hydroxy-1-(5-nitrothiophen-2-yl)methanimine is used as a precursor in synthetic chemistry for the synthesis of various organic molecules. Its unique structure, which includes a nitro group and a thiophene ring, allows for a range of chemical reactions and modifications, making it a versatile building block in the creation of new compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (E)-N-hydroxy-1-(5-nitrothiophen-2-yl)methanimine is used as a potential starting material for drug discovery and development. Its N-hydroxyimine functional group and the presence of a nitro group on the thiophene ring may contribute to its biological activity, making it a promising candidate for further investigation into its potential therapeutic applications.
Used in Drug Discovery:
(E)-N-hydroxy-1-(5-nitrothiophen-2-yl)methanimine is used as a compound of interest in drug discovery due to its potential biological activity. (E)-N-hydroxy-1-(5-nitrothiophen-2-yl)methanimine's unique structure may allow it to interact with biological targets, such as enzymes or receptors, which could lead to the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 6030-18-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,0,3 and 0 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6030-18:
(6*6)+(5*0)+(4*3)+(3*0)+(2*1)+(1*8)=58
58 % 10 = 8
So 6030-18-8 is a valid CAS Registry Number.
6030-18-8Relevant articles and documents
HCl-mediated cascade cyclocondensation of oxygenated arylacetic acids with arylaldehydes: one-pot synthesis of 1-arylisoquinolines
Hsueh, Nai-Chen,Chen, Shin-Mei,Lin, Chun-Yi,Chang, Meng-Yang
, p. 1047 - 1059 (2021/02/16)
In this paper, a concise, open-vessel synthesis of 1-arylisoquinolines is describedviaHCl-mediated intermolecular cyclocondensation of oxygenated arylacetic acids with arylaldehydes in the presence of NH2OH and alcoholic solvents under mild and one-pot reaction conditions. A plausible mechanism is proposed and discussed herein. In the overall reaction process, only water was generated as the byproduct. Various environmentally friendly reaction conditions are investigated for convenient transformationviathe (4C + 1C + 1N) annulation. This protocol provides a highly effective ring closureviathe formations of one carbon-carbon (C-C) bond, two carbon-nitrogen (C-N) bonds and one carbon-oxygen (C-O) bond.
Cascade Process for Direct Transformation of Aldehydes (RCHO) to Nitriles (RCN) Using Inorganic Reagents NH2OH/Na2CO3/SO2F2 in DMSO
Fang, Wan-Yin,Qin, Hua-Li
, p. 5803 - 5812 (2019/05/14)
A simple, mild, and practical process for direct conversion of aldehydes to nitriles was developed feathering a wide substrate scope and great functional group tolerability (52 examples, over 90% yield in most cases) using inorganic reagents (NH2OH/Na2CO3/SO2F2) in DMSO. This method allows for transformations of readily available, inexpensive, and abundant aldehydes to highly valuable nitriles in a pot, atom, and step-economical manner without transition metals. This protocol will serve as a robust tool for the installation of cyano-moieties to complicated molecules.