603128-15-0

Basic information

• Product Name: 3(2H)-Pyridazinone, 5-(2-bromophenyl)-4-phenyl-2-(phenylmethyl)-
• CAS NO: 603128-15-0
• Molecular Formula: C23H17BrN2O
• Molecular Weight: 417.305
• Mol File: 603128-15-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3(2H)-Pyridazinone, 5-(2-bromophenyl)-4-phenyl-2-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3(2H)-Pyridazinone, 5-(2-bromophenyl)-4-phenyl-2-(phenylmethyl)-(603128-15-0)
• EPA Substance Registry System: 3(2H)-Pyridazinone, 5-(2-bromophenyl)-4-phenyl-2-(phenylmethyl)-(603128-15-0)

Safety Data

• Hazardous Substances Data: 603128-15-0(Hazardous Substances Data)

Upstream product

• 603128-13-8 2-benzyl-5-hydroxy-4-phenylpyridazin-3(2H)-one 
• 603128-12-7 2-benzyl-5-methoxy-4-phenylpyridazin-3(2H)-one 
• 40890-47-9 2-benzyl-4-chloro-5-methoxy-2H-pyridazin-3-one 
• 244205-40-1 (2-bromophenyl)boronic acid 
• 603128-14-9 2-benzyl-4-phenyl-5-trifluoromethanesulfonyloxypyridazin-3(2H)-one 

Downstream Products

• 603128-17-2 2-benzyl-dibenzo[f,h]phthalazin-1(2H)-one 

Relevant articles and documents

Synthesis of the dibenzo[f,h]phthalazine and dibenzo[f,h]cinnoline skeleton via a 'Suzuki-Pd-catalyzed intramolecular arylation' and a 'Suzuki-Pschorr' approach

Palladium-catalyzed intramolecular arylation of 2-benzyl-5-(2-bromophenyl)-4-phenylpyridazin-3(2H)-one yielded hitherto unknown 2-benzyldibenzo[f,h]phthalazin-1(2H)-one. The synthesis of this new tetracyclic pyridazinone from 2-benzyl-5-(2-aminophenyl)-4-phenylpyridazin-3(2H)-one via a Pschorr type reaction was also investigated. Similarly, the construction of 2-methyldibenzo[f,h]cinnolin-3(2H)-one from 2-methyl-5-(2-bromophenyl)-6-phenylpyridazin-3(2H)-one and 2-methyl-5-(2-aminophenyl)-6-phenylpyridazin-3(2H)-one is also reported. Removal of the N-benzyl protective group of 2-benzyl-dibenzo[f,h]phthalazin-1(2H)-one with AlCl3 yielded unsubstituted dibenzo[f,h]phthalazin-1(2H)-one.