6036-46-0

Basic information

• Product Name: 2-ethoxy-6-nitrobenzenamine
• Synonyms: 2-ethoxy-6-nitrobenzenamine;2-ETHOXY-6-NITROANILINE
• CAS NO: 6036-46-0
• Molecular Formula: C₈H₁₀N₂O₃
• Molecular Weight: 182.1766
• Mol File: 6036-46-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 59.5-60.5 °C
• Boiling Point: 331.7±22.0 °C(Predicted)
• Appearance: /
• Density: 1.264±0.06 g/cm3(Predicted)
• PKA: -0.41±0.25(Predicted)
• CAS DataBase Reference: 2-ethoxy-6-nitrobenzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethoxy-6-nitrobenzenamine(6036-46-0)
• EPA Substance Registry System: 2-ethoxy-6-nitrobenzenamine(6036-46-0)

Safety Data

• Hazardous Substances Data: 6036-46-0(Hazardous Substances Data)

Upstream product

• 4280-24-4 (2,3-dinitrophenyl)ethylether 
• 7664-41-7 ammonia 
• 603-85-0 2-Amino-3-nitrophenol 
• 75-03-6 ethyl iodide 
• 74-96-4 ethyl bromide 

Downstream Products

• 854254-16-3 (2-ethoxy-6-nitro-phenyl)-(2-nitro-phenyl)-amine 
• 123241-32-7 2-ethoxy-6-nitro-benzonitrile 
• 908355-78-2 2-bromo-3-nitro-phenetole 
• 767583-07-3 7-ethoxy-benzothiazole-2-thiol 
• 908355-80-6 3-ethoxy-2-bromo-aniline 
• 854254-07-2 (2-ethoxy-6-nitro-phenyl)-methyl-(2-nitro-phenyl)-amine 
• 191849-71-5 3-ethoxy-1,2-phenylenediamine 

Relevant articles and documents

Design, Synthesis, Biological Evaluation, and Molecular Modeling of 2-Difluoromethylbenzimidazole Derivatives as Potential PI3Kα Inhibitors

PI3Kα is one of the potential targets for novel anticancer drugs. In this study, a series of 2-difluoromethylbenzimidazole derivatives were studied based on the combination of molecular modeling techniques 3D-QSAR, molecular docking, and molecular dynamic

BENZIMIDAZOLE DERIVATIVES AND USES THEREOF

Benzimidazole derivatives of Formula I, that modulate the activity of ACSS2 are disclosed for therapeutic use. The fused imidazole ring of the compounds disclosed has a diarylmethyl or diarylmethanol moiety attached at the 2-position and the compounds have at least one other substituent at the 5 or 6 position of the benzimidazole. Also disclosed are methods of using the benzimidazole compounds for the treatment of diseases or disorders, such as cancer.