6039-37-8 Usage
Description
(2R,6S)-2,6-PIPERIDINEDICARBOXYLIC ACID DIMETHYL ESTER HYDROCHLORIDE, also known as (-)-Pilocarpine hydrochloride, is a pharmaceutical chemical compound with a piperidine ring structure featuring two carboxylic acid groups and two methyl ester groups. As a hydrochloride salt, it exhibits enhanced stability and water solubility compared to its free base form, which is advantageous for pharmaceutical applications. (2R,6S)-2,6-PIPERIDINEDICARBOXYLIC ACID DIMETHYL ESTER HYDROCHLORIDE functions as a potent muscarinic receptor agonist and has demonstrated utility in various medical treatments.
Uses
Used in Ophthalmology:
(2R,6S)-2,6-PIPERIDINEDICARBOXYLIC ACID DIMETHYL ESTER HYDROCHLORIDE is used as a cholinergic agonist for the treatment of glaucoma. It helps to reduce intraocular pressure by stimulating the secretion of aqueous humor and enhancing outflow through the trabecular meshwork, thereby slowing the progression of vision loss associated with the disease.
Used in Dentistry:
In the field of dentistry, (2R,6S)-2,6-PIPERIDINEDICARBOXYLIC ACID DIMETHYL ESTER HYDROCHLORIDE is used as a medication for treating xerostomia, or dry mouth. It stimulates the salivary glands to increase saliva production, providing relief from the discomfort and potential oral health issues arising from reduced saliva flow.
Used in Cardiovascular Applications:
(2R,6S)-2,6-PIPERIDINEDICARBOXYLIC ACID DIMETHYL ESTER HYDROCHLORIDE is used as a muscarinic receptor agonist for potential applications in controlling heart rate and blood pressure. Its ability to influence these parameters makes it a candidate for research into treatments for various cardiovascular conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 6039-37-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,0,3 and 9 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 6039-37:
(6*6)+(5*0)+(4*3)+(3*9)+(2*3)+(1*7)=88
88 % 10 = 8
So 6039-37-8 is a valid CAS Registry Number.
6039-37-8Relevant articles and documents
Highly selective and facile synthesis of dihydro- and tetrahydropyridine dicarboxylic acid derivatives using electroreduction as a key step
Kita, Yoshio,Maekawa, Hirofumi,Yamasaki, Yasuhiro,Nishiguchi, Ikuzo
, p. 2095 - 2102 (2001)
Electroreduction of pyridinedicarboxylic acid derivatives 1a-g in methanol containing ammonium chloride using a divided cell brought about highly selective hydrogenation to give the corresponding dihydropyridines in good yields. From the electrolysis of d
