603940-91-6

Basic information

• Product Name: DL-2-(5-Bromothienyl)alanine
• Synonyms: DL-2-(5-Bromothienyl)alanine;3-(5-BroMothien-2-yl)-DL-alanine
• CAS NO: 603940-91-6
• Molecular Formula: C7H8BrNO2S
• Molecular Weight: 250.11292
• Mol File: 603940-91-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: DL-2-(5-Bromothienyl)alanine(CAS DataBase Reference)
• NIST Chemistry Reference: DL-2-(5-Bromothienyl)alanine(603940-91-6)
• EPA Substance Registry System: DL-2-(5-Bromothienyl)alanine(603940-91-6)

Safety Data

• Hazardous Substances Data: 603940-91-6(Hazardous Substances Data)

Relevant articles and documents

Improved preparation of racemic 2-amino-3-(heteroaryl)propanoic acids and related compounds containing a furan or thiophene nucleus

Racemic 2-amino-3-(heteroaryl)propanoic acids (1), mostly with a furan or thiophene nucleus as a heteroaryl group, were synthesized in 48-94% yield by the reduction of 3-(heteroaryl)-2-(hydroxyimino)propanoic acids (5) with zinc dust and formic acid in the presence of a catalytic amount of iron dust at 60°C for 2 h. Under these conditions, unfavorable hydrogenolysis of bromine on the thiophene nucleus does not occur. Traditional Nformylation of the prepared 3-(heteroaryl)alanine (1) with a mixture of formic acid and acetic anhydride afforded 2-(formylamino)-3-(heteroaryl)propanoic acids (6) in 51-95% yield.