60441-55-6

Basic information

• Product Name: Benzenemethanol, a-butyl-3-methoxy-
• CAS NO: 60441-55-6
• Molecular Formula: C12H18O2
• Molecular Weight: 194.274
• Mol File: 60441-55-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-butyl-3-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-butyl-3-methoxy-(60441-55-6)
• EPA Substance Registry System: Benzenemethanol, a-butyl-3-methoxy-(60441-55-6)

Safety Data

• Hazardous Substances Data: 60441-55-6(Hazardous Substances Data)

Upstream product

• 693-04-9 butyl magnesium bromide 
• 591-31-1 3-methoxy-benzaldehyde 
• 122-56-5 tributyl borane 
• 85690-31-9 1-(dichloromethyl)-3-methoxybenzene 
• 19350-71-1 N'-(3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide 
• 110-62-3 pentanal 
• 766-85-8 3-methoxy-1-iodobenzene 
• 73686-45-0 pyridin-2-yl 3-methoxybenzoate 
• 42930-39-2 n-butylzinc chloride 
• 586-38-9 3-Methoxybenzoic acid 
• 109-72-8 n-butyllithium 
• 693-03-8 n-butyl magnesium bromide 
• 124-38-9 carbon dioxide 
• 1889-20-9 n-butylmagnesium iodide 

Downstream Products

• 126983-64-0 (E)-1-methoxy-3-(pent-1-en-1-yl)benzene 
• 20056-66-0 3-pentyl phenol 
• 1291093-59-8 1-methoxy-5-pentylcyclohexa-1,4-diene 
• 68266-27-3 5,6-di-(3'-hydroxyphenyl)-decane 
• 68266-36-4 5,6-di-(3'-methoxyphenyl)-decane 
• 92759-34-7 2-Methoxy-6-(1'-hydroxypentyl)phenol 
• 68266-35-3 1-chlor-1-(3'-methoxyphenyl)-pentane 
• 19523-05-8 1-(4-hydroxy-3-methoxy-phenyl)-pentan-1-ol 
• 20056-57-9 1-methoxy-3-pentylbenzene 

Relevant articles and documents

Direct transformation of aryl 2-pyridyl esters to secondary benzylic alcohols by nickel relay catalysis

A direct transformation of aryl esters to secondary benzylic alcohols via tandem Ni-catalyzed cross-coupling reactions of aromatic 2-pyridyl esters with alkyl zinc reagents and carbonyl group reduction by Ni-H species is achieved. Preliminary mechanistic studies reveal that the Ni-H species is generated in situ via β-hydride elimination of the Negishi reagents. The reaction is catalyzed by bench-stable nickel salts under mild conditions with wide functional group tolerance.

Sequential Birch reaction and asymmetric Ir-catalyzed hydrogenation as a route to chiral building blocks

A range of 1,2,4-trisubstituted cyclohexadienes obtained from the Birch reaction were hydrogenated asymmetrically to produce synthetically valuable chiral compounds in high enantio- and diastereoselectivity. The Royal Society of Chemistry.

Inhibitors of protein isoprenyl transferases

Compounds having the formula STR1or a pharmaceutically acceptable salt thereof wherein R 1 is (a) hydrogen, (b) loweralkyl, (c) alkenyl, (d) alkoxy, (e) thioalkoxy, (f) halo, (g) haloalkyl, (h) aryl-L 2 --, and (i) heterocyclic-L 2 --; R 2 is selected from STR2(b) --C(O)NH--CH(R 14)--C(O)OR 15, STR3(d) --C(O)NH--CH(R 14)--C(O)NHSO 2 R 16, (e) --C(O)NH--CH(R 14)-tetrazolyl, (f) --C(O)NH-heterocyclic, and (g) --C(O)NH--CH(R 14)--C(O)NR 17 R 18 ; R 3 is heterocyclic, aryl, substituted or unsubstituted cycloalkyl; R 4 is hydrogen, lower alkyl, haloalkyl, halogen, aryl, arylakyl, heterocyclic, or (heterocyclic)alkyl; L 1 is absent or is selected from (a) --L 4 --N(R 5)--L 5 --, (b) --L 4 --O--L 5 --, (c) --L 4 --S(O) n --L 5 -- (d) --L 4 --L 6 --C(W)--N(R 5)--L 5 --, (e) --L 4 --L 6 --S(O)m--N(R 5)--L 5 --, (f) --L 4 --N(R 5)--C(W)--L 7 --L 5 --, (g) --L 4 --N(R 5)--S(O) p --L 7 --L 5 --, (h) optionally substituted alkylene, (i) optionally substituted alkenylene, and (j) optionally substituted alkynylene are inhibitors of protein isoprenyl transferases. Also disclosed are protein isoprenyl transferase inhibiting compositions and a method of inhibiting protein isoprenyl transferases.