60456-13-5

Basic information

• Product Name: methyl 2-bromo-3-methoxy-3-phenylpropanoate
• CAS NO: 60456-13-5
• Molecular Formula: C₁₁H₁₃BrO₃
• Molecular Weight: 273.1231
• Mol File: 60456-13-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 327.3°C at 760 mmHg
• Flash Point: 151.8°C
• Density: 1.394g/cm³
• Vapor Pressure: 0.000203mmHg at 25°C
• Refractive Index: 1.534
• CAS DataBase Reference: methyl 2-bromo-3-methoxy-3-phenylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-bromo-3-methoxy-3-phenylpropanoate(60456-13-5)
• EPA Substance Registry System: methyl 2-bromo-3-methoxy-3-phenylpropanoate(60456-13-5)

Safety Data

• Hazardous Substances Data: 60456-13-5(Hazardous Substances Data)

Upstream product

• 103-26-4 Methyl cinnamate 
• 67-56-1 methanol 
• 103-26-4 methyl cinnamate 
• 621-82-9 Cinnamic acid 
• 7726-95-6 bromine 
• 140-10-3 (E)-3-phenylacrylic acid 
• 19713-73-6 methyl (2Z)-3-phenylprop-2-enoate 
• 52742-05-9 Methyl(R,R)-2-bromo-3-methoxy-3-phenylpropanoate 

Downstream Products

• 60456-14-6 2-bromo-3-methoxy-3-phenylpropionic acid 
• 133379-85-8 methyl (2R*,3R*)-2--3-methoxy-3-phenylpropanoate 
• 133379-85-8 methyl (2S*,3R*)-2--3-methoxy-3-phenylpropanoate 
• 141320-45-8 rel-(2S,3R)-methyl 2-deuterio-3-methoxy-3-phenylpropanoate 
• 141320-45-8 rel-(2R,3R)-methyl 2-deuterio-3-methoxy-3-phenylpropanoate 
• 52742-05-9 (2R,3S)-2-Bromo-3-methoxy-3-phenyl-propionic acid methyl ester 

Relevant articles and documents

Alkoxybromination of olefins using ammonium bromide and oxone

A mild, efficient, and highly regio- and stereoselective method for the methoxy and ethoxy bromination of olefins has been developed using NH 4Br as a bromine source and Oxone as an oxidant. Various kinds of olefins (aromatic, linear, and cyclic olefins) afforded the corresponding alkoxy brominated products in moderate to excellent yields. Taylor & Francis Group, LLC.

Organocatalysis in the stereoselective bromohydrin reaction of alkenes

An efficient regio- and stereo-selective (>99:1) trans-bromohydrination (bromohydroxylation and bromomethoxylation) of alkenes including α,β-unsaturated carbonyl compounds with N-bromosuccinimide (NBS) has been achieved by using 1.0 mol% of N,N'-diarylthi

NaIO4-Mediated Selective Oxidative Halogenation of Alkenes and Aromatics Using Alkali Metal Halides

(Equation presented) NaIO4 oxidizes alkali metal halides efficiently in aqueous medium to halogenate alkenes and aromatics and produce the corresponding halo derivatives in excellent regio and stereoselectivity. The system also demonstrates the asymmetric version of bromo hydroxylation using β-cyclodextrin complexes, resulting in moderate ee.