6046-63-5 Usage
Description
5-Chloro-35di-O-acetyl-2'-deoxyuridine is a halogenated uridine derivative, which is a type of nucleoside analog. It is a white crystalline solid with unique chemical properties that make it suitable for various applications in the pharmaceutical industry.
Uses
Used in Pharmaceutical Compositions:
5-Chloro-35di-O-acetyl-2'-deoxyuridine is used as an active pharmaceutical ingredient for the development of medications targeting specific diseases. Its unique structure allows it to interact with cellular processes, potentially leading to therapeutic effects.
Used in Antiviral Applications:
In the field of antiviral drug development, 5-Chloro-35di-O-acetyl-2'-deoxyuridine is used as an antiviral agent. Its mechanism of action may involve the inhibition of viral replication by interfering with the synthesis of viral nucleic acids, thus helping to control the spread of the virus within the host.
Used in Anticancer Applications:
5-Chloro-35di-O-acetyl-2'-deoxyuridine is also utilized as an anticancer agent. It may work by disrupting the nucleic acid synthesis in cancer cells, leading to the inhibition of their proliferation and potentially contributing to the treatment of various types of cancer.
Used in Research and Development:
In the research and development sector, 5-Chloro-35di-O-acetyl-2'-deoxyuridine serves as a valuable compound for studying the mechanisms of nucleic acid synthesis and the development of new therapeutic strategies against diseases involving abnormal cell proliferation, such as cancer and viral infections.
Used in Drug Delivery Systems:
To enhance the bioavailability and delivery of 5-Chloro-35di-O-acetyl-2'-deoxyuridine, it can be incorporated into various drug delivery systems, such as nanoparticles or liposomes. These systems aim to improve the compound's stability, solubility, and targeted delivery to specific cells or tissues, thereby increasing its therapeutic efficacy and reducing potential side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 6046-63-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,0,4 and 6 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 6046-63:
(6*6)+(5*0)+(4*4)+(3*6)+(2*6)+(1*3)=85
85 % 10 = 5
So 6046-63-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H15ClN2O7/c1-6(17)21-5-10-9(22-7(2)18)3-11(23-10)16-4-8(14)12(19)15-13(16)20/h4,9-11H,3,5H2,1-2H3,(H,15,19,20)/t9-,10-,11-/m1/s1
6046-63-5Relevant articles and documents
Systematic assignment of NMR spectra of 5-substituted-4-thiopyrimidine nucleosides
Zhang, Xiaohui,Wang, Jian,Xu, Yao-Zhong
, p. 523 - 529 (2013/09/02)
Unambiguous characterization of 5-substituted-4-thiopyrimidine nucleosides (ribonucleosides and 2'-deoxynucleosides) was performed using NMR spectroscopy. Assignments of all proton and carbon signals of 5-bromo-4-thiouridine and related nucleosides were systematically carried out and firmly established by COSY and HMQC techniques. The NMR data of various 4-thiopyrimidine nucleosides are compared, and the key contributing factors discussed. The approach presented here is applicable to other modified nucleosides and nucleotides, as well as nucleobases. Copyright
Ionic liquid mediated synthesis of 5-halouracil nucleosides: Key precursors for potential antiviral drugs
Kumar, Vineet,Malhotra, Sanjay V.
experimental part, p. 821 - 834 (2010/08/20)
Synthesis of antiviral 5-halouracil nucleosides, also used as key precursors for the synthesis of other potential antiviral drugs, has been demonstrated using ionic liquids as convenient and efficient reaction medium.
In-cell Indirect Electrochemical Halogenation of Pyrimidine Bases and their Nucleosides to 5-Haloderivatives
Palmisano, G.,Danieli, B.,Santagostino, M.,Vodopivec, B.,Fiori, G.
, p. 7779 - 7782 (2007/10/02)
Reaction of anodically generated "halonium" species (LiX or Bu4NX, LiClO4, MeCN, Pt/Pt; I2, LiClO4, MeCN) with pyrimidine bases and their nucleosides leads to 5-halo compounds in good yields.
