60467-16-5

Basic information

• Product Name: 4-Isoxazolemethanol, a-(2-chlorophenyl)-3,5-dimethyl-
• CAS NO: 60467-16-5
• Molecular Formula: C12H12ClNO2
• Molecular Weight: 237.686
• Mol File: 60467-16-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Isoxazolemethanol, a-(2-chlorophenyl)-3,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Isoxazolemethanol, a-(2-chlorophenyl)-3,5-dimethyl-(60467-16-5)
• EPA Substance Registry System: 4-Isoxazolemethanol, a-(2-chlorophenyl)-3,5-dimethyl-(60467-16-5)

Safety Data

• Hazardous Substances Data: 60467-16-5(Hazardous Substances Data)

Upstream product

• 10557-85-4 4-iodo-3,5-dimethylisoxazole 
• 89-98-5 2-chloro-benzaldehyde 
• 15725-14-1 3-acetyl-4-(2-chlorophenyl)-3-buten-2-one 

Downstream Products

• 90672-50-7 1-[(2-Chloro-phenyl)-(3,5-dimethyl-isoxazol-4-yl)-methyl]-4-methyl-piperazine 
• 90672-53-0 1-[(2-Chloro-phenyl)-(3,5-dimethyl-isoxazol-4-yl)-methyl]-piperazine 
• 60467-19-8 4-[chloro-(2-chloro-phenyl)-methyl]-3,5-dimethyl-isoxazole 

Relevant articles and documents

Heterocyclic Analogues of Chlorcyclizine with Potent Hypolipidemic Activity

A series of piperazines was synthesized and their effect of reducing serum cholesterol and triglyceride levels in the rat was evaluated.A systematic exploration of the structure-activity relationships led to the synthesis of (R,S)-(3,5-dimethylisoxazol-4-yl)(4-methylpiperazin-1-yl)methane dihydrochloride (M and B 31426), which had potent activity in lowering serum lipid levels at a daily oral dose of 2 mg/kg and was 100 times more potent than clofibrate.