604754-35-0

Basic information

• Product Name: 3-Quinolinecarbonitrile,2-[(2-aminoethyl)amino]-5,7-dimethyl-(9CI)
• Synonyms: 3-Quinolinecarbonitrile,2-[(2-aminoethyl)amino]-5,7-dimethyl-(9CI)
• CAS NO: 604754-35-0
• Molecular Formula: C₁₄H₁₆N₄
• Molecular Weight: 240.30364
• Product Categories: PYRIDINE
• Mol File: 604754-35-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 478.4±45.0 °C(Predicted)
• Appearance: /
• Density: 1.18±0.1 g/cm3(Predicted)
• PKA: 8.87±0.10(Predicted)
• CAS DataBase Reference: 3-Quinolinecarbonitrile,2-[(2-aminoethyl)amino]-5,7-dimethyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Quinolinecarbonitrile,2-[(2-aminoethyl)amino]-5,7-dimethyl-(9CI)(604754-35-0)
• EPA Substance Registry System: 3-Quinolinecarbonitrile,2-[(2-aminoethyl)amino]-5,7-dimethyl-(9CI)(604754-35-0)

Safety Data

• Hazardous Substances Data: 604754-35-0(Hazardous Substances Data)

Upstream product

• 482639-32-7 2-chloro-5,7-dimethylquinoline-3-carbaldehyde 
• 1356485-81-8 C₁₂H₁₁ClN₂O 
• 917747-10-5 2-chloro-5,7-dimethylquinoline-3-carbonitrile 
• 107-15-3 ethylenediamine 
• 2050-45-5 N-acetyl-3,5-dimethylaniline 
• 108-69-0 3,5-dimethylaminoaniline 

Downstream Products

• 1356485-86-3 N-(2-((3-cyano-5,7-dimethylquinolin-2-yl)amino)ethyl)-2,4-dimethoxybenzamide 
• 1356485-88-5 N-(2-((3-cyano-5,7-dimethylquinolin-2-yl)amino)ethyl)-2,6-dimethoxybenzamide 
• 1356485-82-9 N-(2-((3-cyano-5,7-dimethylquinolin-2-yl)amino)ethyl)-4-methoxybenzamide 
• 1100331-31-4 N-(2-((3-cyano-5,7-dimethylquinolin-2-yl)amino)ethyl)-2-methoxybenzamide 
• 1100331-45-0 N-(2-((3-cyano-5,7-dimethylquinolin-2-yl)amino)ethyl)-3,4-dimethoxybenzamide 
• 1100330-67-3 N-(2-((3-cyano-5,7-dimethylquinolin-2-yl)amino)ethyl)benzamide 
• 606101-83-1 N-(2-((3-cyano-5,7-dimethylquinolin-2-yl)amino)ethyl)-3-methoxybenzamide 

Relevant articles and documents

Structure-activity relationships of cyanoquinolines with corrector-potentiator activity in Δf508 cystic fibrosis transmembrane conductance regulator protein

Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel. The most common CF-causing mutation, ΔF508-CFTR, produces CFTR loss-of-function by impairing its cellular targeting to the plas

Cyanoquinolines with independent corrector and potentiator activities restore ΔPhe508-cystic fibrosis transmembrane conductance regulator chloride channel function in cystic fibrosis

The ΔPhe508 mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) protein impairs its folding, stability, and chloride channel gating. Although small molecules that separately correct defective ΔPhe508-CFTR folding/cellular processing