6051-43-0

Basic information

• Product Name: Terephthalic acid monoamide
• Synonyms: 4-CARBOXAMIDOBENZOIC ACID;P-CARBOXYLIC ACID BENZAMIDE;RARECHEM AL BO 0290;TEREPHTHALIC ACID MONOAMIDE;4-(AMINOCARBONYL)BENZOIC ACID;4-CARBOXYLIC ACID BENZAMIDE;4-carbamoylbenzoic acid;4-Carboxybenzamide, Terephthalic acid monoamide, Terephthalamic acid
• CAS NO: 6051-43-0
• Molecular Formula: C₈H₇NO₃
• Molecular Weight: 165.15
• Mol File: 6051-43-0.mol
• Article Data: 15

Chemical Properties

• Melting Point: 248 °C
• Boiling Point: 292.97°C (rough estimate)
• Flash Point: 196 °C
• Appearance: /
• Density: 1.3450 (rough estimate)
• Refractive Index: 1.5468 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.84±0.10(Predicted)
• CAS DataBase Reference: Terephthalic acid monoamide(CAS DataBase Reference)
• NIST Chemistry Reference: Terephthalic acid monoamide(6051-43-0)
• EPA Substance Registry System: Terephthalic acid monoamide(6051-43-0)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 6051-43-0(Hazardous Substances Data)

Usage

General Description

Terephthalic acid monoamide is a chemical compound with the molecular formula C8H7NO3. It is a white crystalline powder used mainly as an intermediate in the production of various polymers, including polyesters and polyamides. terephthalic acid monoamide is formed by the reaction of terephthalic acid with ammonia. It is also used as a precursor in the synthesis of specialty chemicals and pharmaceuticals. This chemical is known for its high melting point and stability at high temperatures, making it suitable for applications in the production of high-performance plastics and fibers. Additionally, terephthalic acid monoamide is considered to be non-toxic and has low environmental impact.

Upstream product

• 619-65-8 4-cyanobenzoic Acid 
• 860563-53-7 4-trichloroacetyl-benzoic acid 
• 7153-22-2 ethyl 4-cyanobenzoate 
• 623-26-7 terephthalonitrile 
• 104-85-8 para-methylbenzonitrile 
• 7722-84-1 dihydrogen peroxide 
• 117260-07-8 4-carboxybenzaldehyde N,N-dimethylhydrazone 
• 20576-83-4 4-(phenoxycarbonyl)benzoic acid 
• 1137-99-1 mono(2-hydroxyethyl) terephthalic acid 
• 106-42-3 para-xylene 
• 619-55-6 para-methylbenzamide 
• 6051-41-8 4-formylbenzamide 
• 18708-46-8 terephthaloyl chloride 

Downstream Products

• 36157-72-9 Terephthalamic acid 1-carboxy-pentyl ester 
• 150-13-0 4-amino-benzoic acid 
• 1091610-31-9 C₂₆H₃₀N₆O₄ 
• 926634-48-2 4-[6-(4-butyl-phenyl)-7-fluoro-1H-indol-2-yl]-benzamide 
• 597561-78-9 4-(1,3-oxazol-2-yl)benzoic acid 
• 1404449-48-4 ethyl 3-(4-(oxazol-2-yl)phenyl)-3-oxopropanoate 
• 1333426-66-6 N-{(S)-[1-(1-cyano-cyclopropyl)-1H-[1,2,3]triazol-4-yl]-cyclohexyl-methyl}-terephthalamide 
• 1409937-67-2 C₂₃H₂₄F₃N₃O₄S 

Relevant articles and documents

A PROCESS FOR THE PREPARATION OF 4-CYANOBENZOYL CHLORIDES

The present invention relates to a process for the preparation of 4-cyanobenzoyl chlorides of formula I through reaction of compounds of formula II with a chlorinating agent.

Arene-ruthenium(II)-phosphine complexes: Green catalysts for hydration of nitriles under mild conditions

Three new arene-ruthenium(II) complexes were prepared by treating [{RuCl(μ-Cl)(η6-arene)}2] (η6-arene = p-cymene) dimer with tri(2-furyl)phosphine (PFu3) and 1,3,5-triaza-7-phosphaadamantane (PTA), respectively to obtain [RuCl2(η6-arene)PFu3] [Ru]-1, [RuCl(η6-arene)(PFu3)(PTA)]BF4 [Ru]-2 and [RuCl(η6-arene)(PFu3)2]BF4 [Ru]-3. All the complexes were structurally identified using analytical and spectroscopic methods including single-crystal X-ray studies. The effectiveness of resulting complexes as potential homogeneous catalysts for selective hydration of different nitriles into corresponding amides in aqueous medium and air atmosphere was explored. There was a remarkable difference in catalytic activity of the catalysts depending on the nature and number of phosphorus-donor ligands and sites available for catalysis. Experimental studies performed using structural analogues of efficient catalyst concluded a structural-activity relationship for the higher catalytic activity of [Ru]-1, being able to convert huge variety of aromatic, heteroaromatic and aliphatic nitriles. The use of eco-friendly water as a solvent, open atmosphere and avoidance of any organic solvent during the catalytic reactions prove the reported process to be truly green and sustainable.

Magnetic Nanoparticle-Supported Cu–NHC Complex as an Efficient and Recoverable Catalyst for Nitrile Hydration

Magnetic nanoparticles supported N-heterocyclic carbene–Cu complex was prepared and authenticated by FT-IR, SEM, EDX, VSM, powder-XRD. The catalytic activity of these magnetically retrievable NPs was investigated for hydration of nitriles as the simplest route for the synthesis of amides in an atom-economical manner. A wide range of nitriles containing various functional groups such as olefin, aldehyde, nitro, carboxylic acid was examined in this transformation to generate their corresponding amides in the aqueous medium. The immobilized catalyst was easily recovered using an external magnet and reused for six times without significant loss of its catalytic activity. Graphical Abstract: [Figure not available: see fulltext.].