6051-88-3Relevant articles and documents
Synthesis of 4H-Chromen-4-one Derivatives by Intramolecular Palladium-Catalyzed Acylation of Alkenyl Bromides with Aldehydes
Yue, Yixia,Peng, Jinsong,Wang, Deqiang,Bian, Yunyun,Sun, Peng,Chen, Chunxia
, p. 5481 - 5486 (2017/05/24)
The palladium-catalyzed intramolecular acylation of alkenyl bromides and aldehydes was developed for an efficient synthesis of 4H-chromen-4-ones. With Pd(PPh3)4/Xphos as the catalyst and K2CO3 as the base, this protocol was applied to synthesize a small library of diversely functionalized flavonoids in moderate to good yields in 1,4-dioxane.