6053-00-5

Basic information

• Product Name: 1,2-Benzenediol,4-[[[2-(4-hydroxyphenyl)ethyl]- amino]methyl]-
• CAS NO: 6053-00-5
• Molecular Formula: C15H17NO3
• Molecular Weight: 259.3
• Mol File: 6053-00-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,2-Benzenediol,4-[[[2-(4-hydroxyphenyl)ethyl]- amino]methyl]- (CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzenediol,4-[[[2-(4-hydroxyphenyl)ethyl]- amino]methyl]- (6053-00-5)
• EPA Substance Registry System: 1,2-Benzenediol,4-[[[2-(4-hydroxyphenyl)ethyl]- amino]methyl]- (6053-00-5)

Safety Data

• Hazardous Substances Data: 6053-00-5(Hazardous Substances Data)

Usage

General Description

1,2-Benzenediol,4-[[[2-(4-hydroxyphenyl)ethyl]- amino]methyl]- is a chemical compound with a complex structure that includes a benzene ring along with hydroxyl and amino groups. The compound is also known as 4-((2-(4-hydroxyphenyl)ethyl)amino)methyl)benzene-1,2-diol and is a derivative of catechol. It is used in the pharmaceutical industry as a building block for the synthesis of various drugs and as a reagent in chemical reactions. The compound has potential applications in the treatment of various medical conditions and may also exhibit antioxidant properties. However, further research is needed to fully understand and harness the potential benefits of this chemical.

Upstream product

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Relevant articles and documents

Synthesis and characterization of norbelladine, a precursor of Amaryllidaceae alkaloid, as an anti-inflammatory/anti-COX compound

Rising ROS and systemic inflammation is often a serious concern in many disease conditions including obesity. Therefore, compounds with both anti-oxidant and anti-inflammatory activities are considered beneficial in preventing/treating several human chronic diseases. Norbelladine is an amine compound, a precursor for Amaryllidaceae alkaloids (e.g., belladine, crinamine, lycorine, and galanthamine) found in plants traditionally used for treating a variety of human diseases. However, little information is available about its potential health effects. Therefore, the amine was first synthesized, and its anti-oxidant and anti-inflammatory activities were investigated in this study. Also, the potential effects of the amine on NF-κB activation were investigated due to the critical involvement of ROS in the activation. Norbelladine was synthesized with more than 60% yield, analyzed by a HPLC method, and verified using NMR spectroscopic method. Then, its radical scavenging activity was investigated using DPPH- and superoxide radical assays. At the concentration of 10 μM, norbelladine was a compound able to quench DPPH-radical by 31% (P a compound to quench radicals, inhibit COX enzymes as well as suppress NF-κB activation at relatively lower concentrations.

A new lead compound for abscisic acid biosynthesis inhibitors targeting 9-cis-epoxycarotenoid dioxygenase

9-cis-Epoxycarotenoid dioxygenase (NCED), a key enzyme in abscisic acid (ABA) biosynthesis, cleaves the olefinic double bond of 9-cis-epoxycarotenoid. Several analogues of nordihydroguaiaretic acid (NDGA) were designed and synthesized, and their efficacy