60562-16-5 Usage
Description
1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is a saturated diacylglycerol (DAG) with myristic acid (14:0) side-chains attached at both the sn-1 and sn-2 positions. It is a white powder with lumps and is considered a possible weak second messenger for the activation of the protein kinase C (PKC).
Uses
1. Used in Biological Research:
1,2-Dimyristoyl-sn-glycerol is used as a research tool for studying the role of diacylglycerol in cellular signaling and the activation of protein kinase C (PKC). Its weak second messenger properties make it a valuable compound for understanding the mechanisms of PKC activation and its downstream effects on cellular processes.
2. Used in Pharmaceutical Development:
1,2-Dimyristoyl-sn-glycerol is used as a starting point for the development of new pharmaceutical compounds targeting protein kinase C (PKC). By understanding the interactions between DAGs and PKC, researchers can design more effective drugs for various therapeutic applications, such as cancer treatment or other diseases where PKC plays a significant role.
3. Used in Analytical Chemistry:
1,2-Dimyristoyl-sn-glycerol can be used as a reference compound in analytical chemistry for the identification and quantification of diacylglycerols in biological samples. Its unique structure and properties make it a useful standard for developing and validating analytical methods for DAG analysis.
4. Used in Lipid Chemistry:
1,2-Dimyristoyl-sn-glycerol is used in lipid chemistry for studying the properties and functions of diacylglycerols in biological systems. Its saturated nature and specific fatty acid composition allow researchers to investigate the effects of lipid structure on membrane properties, enzyme activity, and other cellular processes.
5. Used in Cosmetics and Personal Care:
1,2-Dimyristoyl-sn-glycerol may be used in the cosmetics and personal care industry as an ingredient in various formulations, such as creams, lotions, and other skincare products. Its emollient properties and ability to form stable emulsions can contribute to the texture, feel, and efficacy of these products.
Check Digit Verification of cas no
The CAS Registry Mumber 60562-16-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,5,6 and 2 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 60562-16:
(7*6)+(6*0)+(5*5)+(4*6)+(3*2)+(2*1)+(1*6)=105
105 % 10 = 5
So 60562-16-5 is a valid CAS Registry Number.
60562-16-5Relevant articles and documents
The Chiral Target of Daptomycin Is the 2R,2′S Stereoisomer of Phosphatidylglycerol
Moreira, Ryan,Taylor, Scott D.
, (2021/12/09)
Daptomycin (dap) is an important antibiotic that interacts with the bacterial membrane lipid phosphatidylglycerol (PG) in a calcium-dependent manner. The enantiomer of dap (ent-dap) was synthesized and was found to be 85-fold less active than dap against
Rapid assembly of oligosaccharides: Total synthesis of a glycosylphosphatidylinositol anchor of trypanosoma brucei
Baeschlin, Daniel K.,Chaperon, Andre R.,Charbonneau, Virginie,Green, Luke G.,Ley, Steven V.,Luecking, Ulrich,Walther, Eric
, p. 3423 - 3428 (2007/10/03)
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