606-14-4

Basic information

• Product Name: 2-amino-4-(2-amino-3-hydroxy-phenyl)-4-oxo-butanoic acid
• Synonyms: 3-HYDROXY-L-KYNURENINE;(2S)-2-Amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutyric acid;3-(2-Amino-3-hydroxybenzoyl)-L-alanine;3-Hydroxy-L-kynulenine;3OHKY;(S)-2-Amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid
• CAS NO: 606-14-4
• Molecular Formula: C₁₀H₁₂N₂O₄
• Molecular Weight: 224.24
• Mol File: 606-14-4.mol
• Article Data: 0

Chemical Properties

• Melting Point: 187.5°C (rough estimate)
• Boiling Point: 365.61°C (rough estimate)
• Flash Point: 267.9°C
• Appearance: /
• Density: 1.2995 (rough estimate)
• Vapor Pressure: 1.31E-11mmHg at 25°C
• Refractive Index: 1.6620 (estimate)
• Storage Temp.: 2-8°C
• PKA: 2.16±0.23(Predicted)
• CAS DataBase Reference: 2-amino-4-(2-amino-3-hydroxy-phenyl)-4-oxo-butanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4-(2-amino-3-hydroxy-phenyl)-4-oxo-butanoic acid(606-14-4)
• EPA Substance Registry System: 2-amino-4-(2-amino-3-hydroxy-phenyl)-4-oxo-butanoic acid(606-14-4)

Safety Data

• Hazardous Substances Data: 606-14-4(Hazardous Substances Data)

Usage

Uses

(S)-2-Amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid (CAS# 606-14-4) is metabolite of L-tryptophan. 3-Hydroxy L-kynurenine may be an endogenous oxidative stress generator and a potential endogenous neurotoxin. It is also used by biological study and diagnostic use in biomarker composition for predicting prognosis of diabetes mellitus after bariatric surgery.

InChI:InChI=1/C10H12N2O4/c11-6(10(15)16)4-8(14)5-2-1-3-7(13)9(5)12/h1-3,6,13H,4,11-12H2,(H,15,16)/t6-/m0/s1

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