606-97-3

Basic information

• Product Name: 1-benzyl-2-phenyl-benzene
• Synonyms: 1-benzyl-2-phenyl-benzene;2-(Phenylmethyl)-1,1'-biphenyl;2-Benzyl-1,1'-biphenyl;2-Benzylbiphenyl;o-Benzyldiphenyl;Nsc231615
• CAS NO: 606-97-3
• Molecular Formula: C₁₉H₁₆
• Molecular Weight: 244.33
• Mol File: 606-97-3.mol
• Article Data: 22

Chemical Properties

• Melting Point: 55°C
• Boiling Point: 322.25°C (rough estimate)
• Appearance: /
• Density: 1.0925 (estimate)
• Refractive Index: 1.4750 (estimate)
• CAS DataBase Reference: 1-benzyl-2-phenyl-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-2-phenyl-benzene(606-97-3)
• EPA Substance Registry System: 1-benzyl-2-phenyl-benzene(606-97-3)

Safety Data

• Hazardous Substances Data: 606-97-3(Hazardous Substances Data)

Usage

General Description

1-benzyl-2-phenyl-benzene is a chemical compound with the molecular formula C20H18. It is a member of the benzene family, containing a benzene ring substituted with a benzyl group and a phenyl group. It is a colorless to light yellow liquid at room temperature and is insoluble in water but soluble in organic solvents. 1-benzyl-2-phenyl-benzene is commonly used in the synthesis of various pharmaceuticals and organic compounds. It is also used as a fragrance ingredient and in the production of polymers. Its aromatic properties make it valuable in the formulation of perfumes and other cosmetic products. Additionally, it is used as a precursor in the manufacturing of dyes, pigments, and other industrial chemicals. Due to its aromatic nature and versatile applications, 1-benzyl-2-phenyl-benzene is a valuable compound in the chemical industry.

Upstream product

• 92-52-4 biphenyl 
• 100-44-7 benzyl chloride 
• 118-92-3 anthranilic acid 
• 108-88-3 toluene 
• 16170-82-4 [14C]methyl iodide 
• 101-81-5 Diphenylmethane 
• 100-39-0 benzyl bromide 
• 123-72-8 butyraldehyde 
• 591-51-5 phenyllithium 
• 141819-13-8 n-butyl o-iodobenzyl telluride 
• 1985-32-6 2-phenylbenzophenone 
• 23265-32-9 1-(methylsulfonyl)-2-(phenyl)diazene 
• 17763-65-4 biphenyl-2-yl trifluoromethanesulfonate 
• 13326-10-8 benzyl methyl carbonate 

Downstream Products

• 789-62-8 2-Cyclohexylmethyl-bicyclohexyl 

Relevant articles and documents

Palladium-Catalyzed Cross-Coupling of Superbase-Generated C(sp3) Nucleophiles

A range of methods has been investigated recently for the arylation of weakly acidic C(sp3)-H bonds, primarily exploiting directed metalation with a transition metal catalyst or radical formation via hydrogen atom transfer. In this work, a classical base-mediated approach is taken, exploiting the ability of organometallic superbases to metalate very weakly acidic (pKa> 40) C-H bonds. Conditions are developed with eithern-BuLi/diamine orn-BuLi/KOtBu superbases to enable metalation to occur with high selectivity. Organolithium nucleophiles can be directly used in cross-coupling, or organozincs can be formed to enable reactions with functional group-dense organohalides.

Interactions of C?F Bonds with Hydridoboranes: Reduction, Borylation and Friedel–Crafts Alkylation

The stoichiometric reactions of the alkylfluorides 1-fluoroadamantane (Ad-F), fluorocyclohexane (Cy-F), 1-fluoropentane (Pent-F) and benzyl fluorides with secondary boranes pinacolborane (HBpin), catecholborane (HBcat), 9-borabicyclo(3.3.1)nonane (9-BBN)

A Zwitterionic Palladium(II) Complex as a Precatalyst for Neat-Water-Mediated Cross-Coupling Reactions of Heteroaryl, Benzyl, and Aryl Acid Chlorides with Organoboron Reagents

The Suzuki–Miyaura cross-coupling (SMC) reactions of several heteroaryl chlorides, benzyl chlorides, and aryl acid chlorides with (hetero)arylboron reagents have been investigated in the presence of [Pd(HL1)(PPh3)Cl2] (I) [HL1 = 3-[(2,6-diisopropylphenyl)-1-imidazolio]-2-quinoxalinide] as catalyst and K2CO3 as base in neat water. The synthesis of the heterocycle-containing biaryls required the addition of 2 mol-% of a phosphine ligand (PPh3 or X-Phos). A combination of more than 115 substrates were screened and it was found that I is a versatile catalyst that can produce heterocycle-containing biaryls, diarylmethanes, and benzophenones in moderate-to-excellent yields.