606126-63-0

Basic information

• Product Name: 4,4'-(butane-2,3-diyl)bis(chlorobenzene)
• Synonyms: 4,4'-(butane-2,3-diyl)bis(chlorobenzene)
• CAS NO: 606126-63-0
• Molecular Weight: 279.209
• Mol File: 606126-63-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4,4'-(butane-2,3-diyl)bis(chlorobenzene)(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-(butane-2,3-diyl)bis(chlorobenzene)(606126-63-0)
• EPA Substance Registry System: 4,4'-(butane-2,3-diyl)bis(chlorobenzene)(606126-63-0)

Safety Data

• Hazardous Substances Data: 606126-63-0(Hazardous Substances Data)

Upstream product

• 676-58-4 methylmagnesium chloride 
• 13940-94-8 (4-chlorophenyl)dichloromethane 
• 14804-61-6 1-(1-bromoethyl)-4-chlorobenzene 
• 1073-67-2 4-vinylbenzyl chloride 
• 131-62-4 1-hydroxy-1,2-benzodioxol-3-(1H)-one 
• 637-87-6 1-Chloro-4-iodobenzene 
• 74-85-1 ethene 
• 106-39-8 bromochlorobenzene 

Relevant articles and documents

Ni(II)/Al(0) mediated benzylic Csp 3 - Csp 3 coupling in aqueous media

Abstract : The reaction of benzyl bromides and chlorides with aluminium metal powder or foil (1.2 eqv.) in the presence of catalytic nickel nitrate (10 mol%) in water at room temperature resulted in homocoupling to the corresponding bibenzyl products which were isolated in moderate to good yields. In sharp contrast, the same reaction in organic solvents like dichloromethane, dimethylformamide, acetonitrile, methanol and toluene yielded only a trace amount of the desired product. The scope of the reaction was tested with substituents on the aromatic ring such as Me-, Cl-, CN-, F-, NO 2-, Ph- as well as 2 ° benzyl halides. Graphical abstract: The reagent combination of aluminium metal and catalytic Ni(NO3)2 promotes the homocoupling of benzyl bromides and chlorides giving rise to the corresponding bibenzyl products in good to excellent yields. The reaction is greatly facilitated in water and showed good functional group tolerance. Besides the mild reaction condition and bench-friendliness, the present reaction constitutes the first example of aluminium-mediated homocoupling of a halide in water. [Figure not available: see fulltext.].

Dual Cobalt and Photoredox Catalysis Enabled Intermolecular Oxidative Hydrofunctionalization

A general protocol has been developed for the Markovnikov-selective intermolecular hydrofunctionalization based on visible-light-mediated Co/Ru dual catalysis. The key feature involves the photochemical oxidation of an organocobalt(III) intermediate deriv

Facile reductive coupling of benzylic halides with ferrous oxalate dihydrate

Facile reductive coupling of benzylic halides is reported with ferrous oxalate dihydrate in DMF or HMPA under nitrogen atmosphere at 155-160°C. The coupling is proposed to proceed by two successive oxidative additions of benzylic halides to ferrous oxalate to give an intermediate organoiron complex which undergoes concerted dimerization to give the corresponding reductively coupled dimers in high yields.