606131-61-7

Basic information

• Product Name: 1-Piperidinecarboxamide,N-cyclohexyl-3-hydroxy-(9CI)
• Synonyms: 1-Piperidinecarboxamide,N-cyclohexyl-3-hydroxy-(9CI);N-CYCLOHEXYL-3-HYDROXY-1-PIPERIDINECARBOXAMIDE
• CAS NO: 606131-61-7
• Molecular Formula: C₁₂H₂₂N₂O₂
• Molecular Weight: 226.32
• Product Categories: PIPERIDINE
• Mol File: 606131-61-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Piperidinecarboxamide,N-cyclohexyl-3-hydroxy-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinecarboxamide,N-cyclohexyl-3-hydroxy-(9CI)(606131-61-7)
• EPA Substance Registry System: 1-Piperidinecarboxamide,N-cyclohexyl-3-hydroxy-(9CI)(606131-61-7)

Safety Data

• Hazardous Substances Data: 606131-61-7(Hazardous Substances Data)

Upstream product

• 108-91-8 cyclohexylamine 
• 3173-53-3 Cyclohexyl isocyanate 

Relevant articles and documents

A facile synthesis of unsymmetrical ureas

A facile and versatile method for the synthesis of unsymmetrical ureas from readily available reagents is reported. In the first step trifluoroethylchloroformate is reacted with a stoichiometric amount of a primary amine to give an intermediate trifluoroethyl carbamate. The addition of a second amine (primary or secondary) to the trifluoroethyl carbamate furnishes corresponding unsymmetrical ureas in 75-85% yield. A simple workup procedure, the high yields obtained, and the purity of the isolated products are suitable for the parallel synthesis of combinatorial libraries of unsymmetrical ureas with high structural and functional diversity.