60633-26-3

Basic information

• Product Name: 2-bromo-4,6-dichlorophenyl methyl ether
• Synonyms: 1-bromo-3,5-dichloro-2-methoxybenzene;2-bromo-4,6-dichlorophenyl methyl ether
• CAS NO: 60633-26-3
• Molecular Formula: C₇H₅BrCl₂O
• Molecular Weight: 255.924
• Mol File: 60633-26-3.mol
• Article Data: 2

Chemical Properties

• Melting Point: 65 °C
• Boiling Point: 253-258 °C(Press: 749 Torr)
• Appearance: /
• Density: 1.666±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-bromo-4,6-dichlorophenyl methyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-4,6-dichlorophenyl methyl ether(60633-26-3)
• EPA Substance Registry System: 2-bromo-4,6-dichlorophenyl methyl ether(60633-26-3)

Safety Data

• Hazardous Substances Data: 60633-26-3(Hazardous Substances Data)

Upstream product

• 860243-14-7 4-bromo-2,6-dichloro-3-methoxy-benzaldehyde 
• 4524-77-0 2-bromo-4,6-dichlorophenol 
• 77-78-1 dimethyl sulfate 
• 56962-14-2 2,6-dichloro-3-hydroxybenzaldehyde 
• 56962-10-8 2-chloro-3-hydroxybenzaldehyde 
• 860243-44-3 4-bromo-2-chloro-3-hydroxy-benzaldehyde 
• 873983-87-0 4-bromo-2,6-dichloro-3-hydroxy-benzaldehyde 
• 120-83-2 2,4-dichlorophenol 
• 108-95-2 phenol 
• 74-88-4 methyl iodide 
• 553-82-2 1,3-dichloro-4-methoxybenzene 

Downstream Products

• 871879-43-5 2-bromo-4,6-dichloro-3,5-dinitro-anisole 

Relevant articles and documents

Triptycenyl Sulfide: A Practical and Active Catalyst for Electrophilic Aromatic Halogenation Using N-Halosuccinimides

A Lewis base catalyst Trip-SMe (Trip = triptycenyl) for electrophilic aromatic halogenation using N-halosuccinimides (NXS) is introduced. In the presence of an appropriate activator (as a noncoordinating-anion source), a series of unactivated aromatic compounds were halogenated at ambient temperature using NXS. This catalytic system was applicable to transformations that are currently unachievable except for the use of Br2 or Cl2: e.g., multihalogenation of naphthalene, regioselective bromination of BINOL, etc. Controlled experiments revealed that the triptycenyl substituent exerts a crucial role for the catalytic activity, and kinetic experiments implied the occurrence of a sulfonium salt [Trip-S(Me)Br][SbF6] as an active species. Compared to simple dialkyl sulfides, Trip-SMe exhibited a significant charge-separated ion pair character within the halonium complex whose structural information was obtained by the single-crystal X-ray analysis. A preliminary computational study disclosed that the πsystem of the triptycenyl functionality is a key motif to consolidate the enhancement of electrophilicity.