60648-70-6

Basic information

• Product Name: BIS(TRI-T-BUTYLPHOSPHINE)PLATINUM(0)
• Synonyms: BIS(TRI-T-BUTYLPHOSPHINE)PLATINUM(0);BIS(TRI-T-BUTYLPHOSPHINE)PLATINUM(O);BIS-(TRI-TERT-BUTYLPHOSPHINE)PLATINUM(0);Bis(tri-t-butylphosphine)platinum(O),98%;Bis(tri-t-butylphosphine)platinum (0), 98%;Bis(tri-t-butylphosphine)platinuM (0),98% Pt[P(C4H9)3]2;Bis(tri-tert-butylphosphine)platinum;Bis[tris(1,1-dimethylethyl)phosphine]platinum
• CAS NO: 60648-70-6
• Molecular Formula: C₂₄H₅₄P₂Pt
• Molecular Weight: 599.71
• Product Categories: Catalysts for Organic Synthesis;Classes of Metal Compounds;Homogeneous Catalysts;Metal Complexes;Pt (Platinum) Compounds;Synthetic Organic Chemistry;Transition Metal Compounds;Catalysis and Inorganic Chemistry;Chemical Synthesis;Platinum;organometallic complex;Pt
• Mol File: 60648-70-6.mol
• Article Data: 10

Chemical Properties

• Melting Point: 260-269 °C
• Boiling Point: 229.4 °C at 760 mmHg
• Flash Point: 94.6 °C
• Appearance: yellow/Powder
• Vapor Pressure: 0.105mmHg at 25°C
• Storage Temp.: 2-8°C
• Sensitive: air sensitive
• CAS DataBase Reference: BIS(TRI-T-BUTYLPHOSPHINE)PLATINUM(0)(CAS DataBase Reference)
• NIST Chemistry Reference: BIS(TRI-T-BUTYLPHOSPHINE)PLATINUM(0)(60648-70-6)
• EPA Substance Registry System: BIS(TRI-T-BUTYLPHOSPHINE)PLATINUM(0)(60648-70-6)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 60648-70-6(Hazardous Substances Data)

Usage

Description

BIS(TRI-T-BUTYLPHOSPHINE)PLATINUM(0) is a platinum-based organometallic compound with the chemical formula Pt(P(t-Bu)3)2. It is a versatile and valuable catalyst in various chemical reactions due to its unique electronic and steric properties.

Uses

Used in Catalyst Industry:
BIS(TRI-T-BUTYLPHOSPHINE)PLATINUM(0) is used as a catalyst for the synthesis of various organic compounds, including:
1. Trimetallic ReBiPt complexes: It serves as a catalyst for the formation of these complexes, which have potential applications in catalysis and materials science.
2. Rhodium-germanium carbonyl complexes: It is used as a catalyst in the synthesis of these complexes, which can be employed in various catalytic processes.
Used in Pharmaceutical Industry:
BIS(TRI-T-BUTYLPHOSPHINE)PLATINUM(0) is used as a catalyst for the synthesis of:
1. Amidobipyridyl inhibitors of protein kinase D: These inhibitors are important for the development of drugs targeting protein kinase D, which plays a role in various cellular processes and diseases.
2. 5-Fluoroalkylated pyrimidine nucleosides: It acts as a catalyst in the Negishi cross-coupling reaction for the synthesis of these nucleosides, which have potential applications in the development of antiviral and anticancer drugs.
Used in Organometallic Chemistry:
BIS(TRI-T-BUTYLPHOSPHINE)PLATINUM(0) is used as a catalyst for phenyl and methyl group transfer from tin to iridium, which is an important reaction in the synthesis of organoiridium complexes with potential applications in homogeneous catalysis.
Used in Coordination Chemistry:
BIS(TRI-T-BUTYLPHOSPHINE)PLATINUM(0) is used as an activator of metal hydride complexes, which can enhance the reactivity and catalytic activity of these complexes in various chemical transformations.

InChI:InChI=1/2C12H27P.Pt/c2*1-10(2,3)13(11(4,5)6)12(7,8)9;/h2*1-9H3;

Upstream product

• 67901-08-0 trans-bis(tri-tert-butylphosphine)chlorohydridoplatinum(II) 
• 80482-47-9 Tris((tert-butylimino){tert-butyl(trimethylsilyl)amino}phosphane)platinum⁽⁰⁾ 
• 13716-12-6 tri-tert-butyl phosphine 
• 67870-05-7 trans-bis(tri-tert-butylphosphine)platinum(II) dihydride 
• 67871-27-6 trans-PtHBr[P(t-Bu)3]2 
• 12120-15-9 ethylenebis(triphenylphosphine)platinum⁽⁰⁾ 
• 10025-99-7 potassium tetrachloroplatinate(II) 
• 85931-06-2 {PtH(NH₃)(P(C(CH₃)3)3)2}⁽¹⁺⁾*PF₆^(1-)={PtH(NH₃)(P(C(CH₃)3)3)2}PF₆ 
• 85944-38-3 {PtH(NH₃)(P(C(CH₃)3)3)2}⁽¹⁺⁾*ClO₄^(1-)={PtH(NH₃)(P(C(CH₃)3)3)2}ClO₄ 
• 67950-30-5 PtHI(P(CH₃)9C₃)2 
• 86773-84-4 trans-(PtH(P(t-Bu)3)2)ClO₄ 
• 81476-54-2 trans-PtH(ONO₂)[P(t-Bu)3]2 
• 67871-28-7 trans-PtH(CF₃CO₂)[P(t-Bu)3]2 
• 12080-32-9 dichloro( 1,5-cyclooctadiene)platinum(ll) 

Downstream Products

• 915404-61-4 PtOs(CO)4(SnPh3)(PBu(t)3)[μ-H2CCPh] 
• 944391-17-7 PtRu(CO)4(SnPh3)(PBu(t)3)[μ-H2CCPh] 

Relevant articles and documents

A CONVENIENT SYNTHESIS OF BIS(TRI-t-BUTYLPHOSPHINE)PLATINUM(0) AND ITS OXIDATIVE ADDITION AND LIGAND EXCHANGE REACTIONS

Pt2 (I) is prepared in high yield from a facile reaction of P(t-Bu)3 with K2PtCl4.Its oxidative addition reactions with CHCl3, CH2Cl2, MeI, and I2, and substitution reactions with CO, M(CO)6 (M=Cr, Mo, W), and t-BuNC have been investigated.Reaction with CHCl3 affords trans-PtHCl2 (II) and (III), and reaction with CH2Cl2 yields (IV).Pt2Me2(μ-I)22 (VI) and P(t-Bu)3MeI are formed in the reaction of I with MeI.VI undergoes intramolecular metalation to give (V), and CH4.Reaction of I with I2 results in the formation of V, trans-PtHI2 (VII) and P(t-Bu)3I2.CO readily displaces one phosphine from I to give Pt33(CO)3 (VIII).I reacts with M(CO)6 to afford VIII and M(CO)5P(t-Bu)3. t-BuNC replaces both the phosphines from I to give Pt3(t-BuNC)3(μ-t-BuNC)3 (IX).

A Molecular Rotor Possessing an H-M-H "spoke" on a P-M-P "axle": A Platinum(II) trans-Dihydride Spins Rapidly even at 75 K

A new class of low-barrier molecular rotors, metal trans-dihydrides, is suggested here. To test whether rapid rotation can be achieved, the known complex trans-H2Pt(PtBu3)2 was experimentally studied by 2H and 195Pt solid-state NMR spectroscopy (powder pattern changes with temperature) and computationally modeled as a tBu3P-Pt-PtBu3 stator with a spinning H-Pt-H rotator. Whereas the related chloro-hydride complex, trans-H(Cl)Pt(PtBu3)2, does not show rotational behavior at room temperature, the dihydride trans-H2Pt(PtBu3)2 rotates fast on the NMR time scale, even at low temperatures down to at least 75 K. The highest barrier to rotation is estimated to be ～3 kcal mol-1, for the roughly 3 ? long rotator in trans-H2Pt(PtBu3)2.

Unexpected substitution reactions of bis(phosphine)platinum ethene complexes

Reaction of [Pt(C2H4)(PR3)2] (R = Ph or C6H4Me-4) with moderately bulky phosphines at low temperatures did not give the expected tris- or tetrakis-phosphine complexes. Instead, mixed-phosph