60657-93-4Relevant articles and documents
2-Methoxycarbonyl-3-prenyl-1,4-naphthoquinone, a Metabolite related to the Biosynthesis of Mollugin and Anthraquinones in Galium mollugo L.
Heide, Lutz,Leistner, Eckhard
, p. 334 - 336 (1981)
The structure of 2-methoxycarbonyl-3-prenyl-1,4-naphthoquinone, isolated from Galium mollugo plants, has been elucidated by spectroscopic methods, synthesis, and derivatisation.
New mollugin analogues and their antioxidant and antibacterial activities
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Paragraph 0035; 0095-0101, (2021/05/31)
The present invention relates to a new mollugin analogue and medical use thereof and, more specifically to newly synthesized mollugin analogues having both antibacterial and antioxidant activities, which can be effectively used as a medicine for oxidation-related diseases or as an antibacterial agent.
Synthesis of novel and diverse mollugin analogues and their antibacterial and antioxidant activities
Idhayadhulla, Akber,Xia, Likai,Lee, Yong Rok,Kim, Sung Hong,Wee, Young-Jung,Lee, Chong-Soon
, p. 77 - 82 (2014/01/17)
Novel and diverse mollugin analogues (1-12) were synthesized using PhB(OH)2/AcOH-mediated electrocyclization reaction as a key step. The newly synthesized compounds were screened for antioxidant and antibacterial activities. Compounds 1, 2, 5, 6, 8, and 10-12 showed high antioxidant activities in DPPH inhibition (IC50 = 0.52-1.11 μM) compared with BHT (IC50 = 9.67 μM). Compounds 3 exhibited potent antibacterial activity against Staphylococcus aureus (KCTC-1916) bacterial strain at 100 μg/mL. Structures of newly synthesized compounds were confirmed by IR, 1H NMR, 13C NMR data and high-resolution mass spectrometry.