60683-15-0 Usage
General Description
DOXYCYCLINE SULFO-SALICYLATE is a combination of two chemicals: doxycycline, an antibiotic, and sulfo-salicylate, a nonsteroidal anti-inflammatory drug (NSAID). This combination medication is used to treat a variety of bacterial infections, particularly those caused by susceptible strains of bacteria. Doxycycline works by inhibiting the growth of bacteria, while sulfo-salicylate reduces inflammation and pain associated with the infection. This combination medication is typically administered orally and is generally well-tolerated, although it may cause some side effects such as nausea, vomiting, and diarrhea. It is important to follow the dosage instructions provided by a healthcare professional and to complete the full course of treatment to ensure the infection is properly treated.
Check Digit Verification of cas no
The CAS Registry Mumber 60683-15-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,6,8 and 3 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 60683-15:
(7*6)+(6*0)+(5*6)+(4*8)+(3*3)+(2*1)+(1*5)=120
120 % 10 = 0
So 60683-15-0 is a valid CAS Registry Number.
InChI:InChI=1/C22H24N2O8.C7H6O6S/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;8-6-2-1-4(14(11,12)13)3-5(6)7(9)10/h4-7,10,14-15,17,25-27,31-32H,23H2,1-3H3;1-3,8H,(H,9,10)(H,11,12,13)/b21-13-;
60683-15-0Relevant articles and documents
Preparation method of doxycycline hydrochloride intermediate hydride
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Paragraph 0026; 0029; 0030; 0031; 0034; 0035, (2017/07/19)
The invention discloses a preparation method of a doxycycline hydrochloride intermediate hydride. The preparation method comprises adding dried oxytetracycline chloride into a dehydration pot containing HF, carrying out reaction dehydration, carrying out standing, evaporating and concentrating to remove HF, collecting the concentrated solution through methanol, neutralizing the methanol solution containing the concentrated solution through calcium hydroxide or calcium oxide powder, carrying out a hydrogenation reaction process on the neutralized methanol solution in the presence of a Pd/C catalyst and an inhibitor, filtering the reaction product, and carrying out a salt formation reaction process on the filtrate and a sulfonyl salicylate methanol solution to obtain the doxycycline hydrochloride intermediate hydride. The preparation method is free of p-toluenesulfonic acid, has simple processes, can be operated easily and greatly reduces a production cost.
