607744-56-9

Basic information

• Product Name: tert-butyl 4-(4-chloro-2-methoxyphenyl)-3,6-dihydropyridine-1(2H)-carboxylate
• Synonyms: tert-butyl 4-(4-chloro-2-methoxyphenyl)-3,6-dihydropyridine-1(2H)-carboxylate
• CAS NO: 607744-56-9
• Molecular Weight: 323.82
• Mol File: 607744-56-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-(4-chloro-2-methoxyphenyl)-3,6-dihydropyridine-1(2H)-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(4-chloro-2-methoxyphenyl)-3,6-dihydropyridine-1(2H)-carboxylate(607744-56-9)
• EPA Substance Registry System: tert-butyl 4-(4-chloro-2-methoxyphenyl)-3,6-dihydropyridine-1(2H)-carboxylate(607744-56-9)

Safety Data

• Hazardous Substances Data: 607744-56-9(Hazardous Substances Data)

Upstream product

• 174913-09-8 2-bromo-5-chloroanisole 
• 375853-82-0 tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinecarboxylate 
• 162046-38-0 1-tert-butyloxycarbonyl-4-trimethylstannyl-1,2,5,6-tetrahydropyridine 

Downstream Products

• 947614-73-5 tert-butyl 4-(4-chloro-2-methoxyphenyl)piperidine-1-carboxylate 
• 815618-53-2 4-(4-chloro-2-methoxyphenyl)piperidine 
• 607744-57-0 tert-butyl 4-{2-methoxy-4-[(1E)-3-morpholin-4-yl-3-oxoprop-1-enyl]phenyl}-3,6-dihydropyridine-1(2H)-carboxylate 

Relevant articles and documents

Substituted aryl or heteroarylpiperidine derivatives as melanocortin-4 receptor modulators

The present invention relates to substituted aryl or heteroarylpiperidine derivatives of structure (I) as melanocortin-4 receptor modulators. Depending on the structure and the stereochemistry the compounds of the invention are either selective agonists or selective antagonists of the human melanocortin-4 receptor (MC-4R). The agonists can be used for the treatment of disorders and diseases such as obesity, diabetes and sexual dysfunction, whereas the antagonists are useful for the treatment of disorders and diseases such as cancer cachexia, muscle wasting, anorexia, anxiety and depression. Generally all diseases and disorders where the regulation of the MC-4R is involved can be treated with the compounds of the invention.

Substituted phenylpiperidine derivatives as melanocortin-4 receptor modulators

The present invention relates to substituted phenylpiperidine derivatives as melanocortin-4 receptor modulators. Depending on the structure and the stereochemistry the compounds of the invention are either selective agonists or selective antagonists of the human melanocortin-4 receptor (MC-4R). The agonists can be used for the treatment of disorders and diseases such as obesity, diabetes and sexual dysfunction, whereas the antagonists are useful for the treatment of disorders and diseases such as cancer cachexia, muscle wasting, anorexia, anxiety and depression. Generally, all diseases and disorders where the regulation of the MC-4R is involved can be treated with the compounds of the invention.