608119-82-0

Basic information

• Product Name: 4-Benzyloxy-3-Methylacetophenone
• Synonyms: 4-Benzyloxy-3-Methylacetophenone;1-[2-methyl-4-(phenylmethoxy)phenyl]Ethanone;1-[4-(benzyloxy)-2-methylphenyl]ethanone
• CAS NO: 608119-82-0
• Molecular Formula: C₁₆H₁₆O₂
• Molecular Weight: 240.29704
• Mol File: 608119-82-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 392.7 °C at 760 mmHg
• Flash Point: 175.5 °C
• Appearance: /
• Density: 1.082 g/cm³
• CAS DataBase Reference: 4-Benzyloxy-3-Methylacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Benzyloxy-3-Methylacetophenone(608119-82-0)
• EPA Substance Registry System: 4-Benzyloxy-3-Methylacetophenone(608119-82-0)

Safety Data

• Hazardous Substances Data: 608119-82-0(Hazardous Substances Data)

Upstream product

• 875-59-2 4'-hydroxy-2'methylacetophenone 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 

Downstream Products

• 1000369-03-8 1-[4-(benzyloxy)-3-bromo-2-methylphenyl]ethanone 
• 957774-00-4 1-[4-(benzyloxy)-5-bromo-2-methylphenyl]ethanone 
• 940099-13-8 ethyl 4-benzyloxy-2-methylbenzoylacetate 
• 78326-88-2 5-benzyloxy-1-indanone 
• 1265683-80-4 1-(4-(benzyloxy)-2-methylphenyl)-2,2-dibromoethanone 
• 1265683-77-9 2-(4-(benzyloxy)-2-methylphenyl)-2-oxoethyl formate 
• 1292299-02-5 2-(4-(benzyloxy)-2-methylphenyl)-2-oxoethyl-4-(tert-butoxycarbonylamino)butanoate 
• 1292299-03-6 2-(4-hydroxy-2-methylphenyl)-2-oxoethyl-4-(tert-butoxycarbonylamino)butanoate 
• 1292298-73-7 4-(2-(4-hydroxy-2-methylphenyl)-2-oxoethoxy)-4-oxobutan-1-aminium-2,2,2-trifluoroacetate 
• 1033723-27-1 [4-(benzyloxy)-5-bromo-2-methylphenyl](4-methoxyphenyl)methanol 
• 957774-50-4 (1S)-1,5-anhydro-2,3,4,6-tetra-O-benzyl-1-[2-(benzyloxy)-5-[4-[2-[[[(2-hydroxy-1,1-dimethylethyl)amino]carbonyl]amino]ethyl]benzyl]-4-methylphenyl]-D-glucitol 
• 957774-51-5 (1S)-1,5-anhydro-2,3,4,6-tetra-O-benzyl-1-[2-(benzyloxy)-5-[4-[2-[[[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]carbonyl]amino]ethyl]benzyl]-4-methylphenyl]-D-glucitol 
• 1033723-28-2 (4-(benzyloxy)-5-bromo-2-methylphenyl)(4-ethylphenyl)methanol 
• 1033723-45-3 1-(benzyloxy)-2-bromo-5-methyl-4-(4-methoxybenzyl)benzene 

Relevant articles and documents

1,4-Palladium Shift/C(sp3)-H Activation Strategy for the Remote Construction of Five-Membered Rings

1,n-Metal shift is an elegant alternative approach enabling the functionalization of remote C-H bonds from simple precursors. In this work, we report a novel and simple Pd0-catalyzed domino reaction involving 1,4-palladium shift and C(sp3)-H activation and leading to (fused) five-membered rings. This method allowed access to a broad range of valuable arylidene γ-lactams and indanones and was applied to the formal synthesis of (-)-pyrrolam.

The power of solvent in altering the course of photorearrangements

A clean bifurcation between two important photochemical reactions through competition of a triplet state Type II H-abstraction reaction with a photo-Favorskii rearrangement for (o/p)-hydroxy-o-methylphenacyl esters that depends on the water content of the solvent has been established. The switch from the anhydrous Type II pathway that yields indanones to the aqueous-dependent pathway producing benzofuranones occurs abruptly at low water concentrations (～8%). The surprisingly clean yields suggest that such reactions are synthetically promising.

C-PHENYL 1-THIOGLUCITOL COMPOUND

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