608523-94-0Relevant articles and documents
Microwave-Assisted Synthesis, Antimicrobial, and Cytotoxicity Activity of N-tert-butyl-3-{[2-(arylamino)pyrimidin-4-yl]amino} Benzenesulfonamides
Patwari, Shivaji B.,Murali, Medari S.,Jadhav, Vivekanand B.
, p. 2911 - 2918 (2018)
A novel synthetic method has been developed with palladium-catalyzed Buchwald–Hartwig-type reaction for the synthesis of N-tert-butyl-3-{[2-(arylamino)pyrimidin-4-yl]amino} benzenesulfonamide 5 by the treatment of N-tert-butyl-3-[(2-chloropyrimidin-4-yl)a
Diphenylamino pyrimidine compound for inhibiting kinase activity
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, (2019/02/04)
The invention provides a diphenylamino pyrimidine compound for inhibiting the kinase activity, and particularly provides a medicinal composition of a substituted diphenylamino pyrimidine compound andapplication thereof. The compound is a compound as shown in a formula (I) in the specification, or pharmaceutically acceptable salt, prodrug, hydrate thereof or solvent compound, crystal form, N-oxideand various diastereomers thereof. The compound can be used for treating diseases which can be treated with JAK2 kinase inhibitors.