60860-35-7Relevant articles and documents
α-Oxygenation of Aldehydes and Cyclic Ketones by Acylation-Rearrangement of Nitrones
Cummins, Clark H.,Coates, Robert M.
, p. 2070 - 2076 (2007/10/02)
The reaction of N-tert-butylnitrones (1a-e) of aldehydes and N-methylnitrones (2 and 3) of cyclic ketones with acid chlorides in the presence of triethylamine afforded α-acyloxy imines by rearrangement of N-vinyl-O-acylhydroxylamine intermediates.Hydrolysis of the α-acyloxy imines gave α-acyloxy aldehydes and ketones.The acylation-rearrangement reaction offers a new method for α-oxygenation of carbonyl compounds.
Chemistry of ketene acetals IV. A simple and general method for the preparation of 4-hydroxy-γ-butyrolactones and 2-butenolides from 1,1-dimethoxypropene and α-acyloxy aldehydes and ketones
Aben, R. W.,Hofstraat, R.,Scheeren, J. W.
, p. 355 - 359 (2007/10/02)
α-Acyloxy aldehydes (2a,b) react with 1,1-dimethoxypropene (1) in the presence of ZnCl2 to yield 2,2-dimethoxy-3-methyloxetanes (3a,b).Stronger electron-withdraving acyl groups are necessary for the analogous conversion of α-acyloxy ketones (2c,d,e).Hydro
