60893-38-1

Basic information

• Product Name: Benzene, 1-chloro-4-[(4-methoxyphenyl)sulfonyl]-
• CAS NO: 60893-38-1
• Molecular Formula: C13H11ClO3S
• Molecular Weight: 282.748
• Mol File: 60893-38-1.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzene, 1-chloro-4-[(4-methoxyphenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-chloro-4-[(4-methoxyphenyl)sulfonyl]-(60893-38-1)
• EPA Substance Registry System: Benzene, 1-chloro-4-[(4-methoxyphenyl)sulfonyl]-(60893-38-1)

Safety Data

• Hazardous Substances Data: 60893-38-1(Hazardous Substances Data)

Upstream product

• 20912-69-0 (4-chlorophenyl)-(4-methoxyphenyl)sulfane 
• 108-90-7 chlorobenzene 
• 98-68-0 4-methoxy-phenyl-sulphonyl chloride 
• 67-56-1 methanol 
• 80-07-9 4,4'-dichlorodiphenyl sulphone 
• 696-62-8 para-iodoanisole 
• 14752-66-0 sodium p-chlorobenzenesulphinate 
• 5720-07-0 4-methoxyphenylboronic acid 
• 459-64-3 4-methoxybenzenediazonium tetrafluoroborate 
• 98-60-2 4-chlorobenzenesulfonyl chloride 
• 2751-25-9 p-chlorophenylsulfonyl hydrazide 
• 106-54-7 p-Chlorothiophenol 
• 100-03-8 4-chlorobenzenesulfinic acid 
• 104-94-9 4-methoxy-aniline 

Downstream Products

• 3112-80-9 bis(p-anisyl)sulfone 

Relevant articles and documents

Heterogeneous copper-catalyzed synthesis of diaryl sulfones

A carbon-supported copper nanoparticle (Cu-NP) with high catalytic activity for the synthesis of diaryl sulfones is reported. For the first time, this Cu-NP is proved to be able to effectively promote the reaction of arylboronic acids and arylsulfonyl hydrazides to generate diaryl sulfones at room temperature. The reaction shows excellent substrate universality, and substrates with different substituents can undergo the reaction smoothly, leading to the desired products in good yields. The Cu-NP is found to be made of low valence Cu based on XRD. Hence, the reaction catalyzed by the Cu-NP is believed to involve a Cu-mediated organometallic cycle.

Organic photoredox catalysis enabled cross-coupling of arenediazonium and sulfinate salts: Synthesis of (un)symmetrical diaryl/alkyl aryl sulfones

We disclose herein the first transition-metal-and external oxidant/reductant-free visible-light-mediated synthesis of (un)symmetrical diaryl/alkyl aryl sulfones from arenediazonium tetrafluoroborates and sodium sulfinates using eosin Y as an organic photoredox catalyst. The utilization of visible light as an inexpensive and ecosustainable energy source, operational simplicity, ambient temperature and clean reaction in aqueous acetonitrile are the salient features of the developed protocol. The desired sulfones were also synthesized via a one-pot, two-step process directly from anilines and sulfinate salts in good to excellent yields.

Visible-Light Photoredox/Nickel Dual Catalysis for the Cross-Coupling of Sulfinic Acid Salts with Aryl Iodides

An efficient cross-coupling of sodium or lithium sulfinates with aryl iodides, using a combination of nickel and photoredox catalysis, is described. The dual catalyst system enables a versatile synthesis of aryl sulfones at room temperature in good yields and displays a broad functional group compatibility. The potential utility of this method in the late-stage diversification of complex molecules and in the conversion of organolithium reagents and sulfur dioxide into sulfones is demonstrated.