60903-54-0

Basic information

• Product Name: Urea, N,N''-(4-methyl-1,3-phenylene)bis[N'-phenyl-
• CAS NO: 60903-54-0
• Molecular Formula: C21H20N4O2
• Molecular Weight: 360.415
• Mol File: 60903-54-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Urea, N,N''-(4-methyl-1,3-phenylene)bis[N'-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Urea, N,N''-(4-methyl-1,3-phenylene)bis[N'-phenyl-(60903-54-0)
• EPA Substance Registry System: Urea, N,N''-(4-methyl-1,3-phenylene)bis[N'-phenyl-(60903-54-0)

Safety Data

• Hazardous Substances Data: 60903-54-0(Hazardous Substances Data)

Upstream product

• 95-80-7 4-methylbenzene-1,3-diamine 
• 103-71-9 phenyl isocyanate 
• 62-53-3 aniline 
• 584-84-9 2,4-Toluene diisocyanate 
• 6935-99-5 2,4-bis(methoxycarbonylamino)toluene 

Downstream Products

• 102-07-8 bis(diphenyl)urea 

Relevant articles and documents

Synthesis and antitussive activity of obtucarbamate A derivatives

Obtucarbamate A was purified from Disporum cantoniense with good antitussive property. In present work, a series of obtucarbamate A derivatives were designed and synthesized from obtucarbamate A by microwave method, and their antitussive activity were evaluated. The results showed that the toluene diisocyanate was obtained with a yield of 95.1percent using a simple method, 1-methyl-2-pyrrolidinone as solvent, temperature of 190 °C, microwave irradiation at 60 W power for 30 min. All compounds have good antitussive activity, and small steric hindrance unsaturated groups of ester chains and amino groups favor activity. It is the first reported of obtucarbamate A derivatives used as antitussive, and the results provide a basis for the application of obtucarbamate derivatives as new antitussive.