60924-38-1 Usage
Description
2-[(Methylsulfonyl)oxy]acetic acid (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester is a complex organic compound with a unique molecular structure. It is a derivative of Pleuroutillin, an antibiotic substance produced by the basidiomycetes Pleurotus mutilus. 2-[(Methylsulfonyl)oxy]acetic acid (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester has a wide range of applications in various industries due to its unique properties and characteristics.
Uses
Used in Pharmaceutical Industry:
2-[(Methylsulfonyl)oxy]acetic acid (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester is used as an intermediate in the synthesis of Retapamulin, an antibacterial agent. Retapamulin is used as a substitute for the more commonly known Penicillin, offering an alternative treatment option for bacterial infections.
Used in Chemical Synthesis:
2-[(Methylsulfonyl)oxy]acetic acid (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester is also used in the synthesis of various other organic compounds and pharmaceuticals. Its unique structure and functional groups make it a valuable building block for the development of new drugs and chemicals with potential therapeutic applications.
Used in Research and Development:
2-[(Methylsulfonyl)oxy]acetic acid (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester is utilized in research and development for the study of its chemical properties, potential applications, and mechanisms of action. This research can lead to the discovery of new uses and applications for this compound in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 60924-38-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,9,2 and 4 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 60924-38:
(7*6)+(6*0)+(5*9)+(4*2)+(3*4)+(2*3)+(1*8)=121
121 % 10 = 1
So 60924-38-1 is a valid CAS Registry Number.
InChI:InChI=1/C23H36O7S/c1-7-21(4)12-17(30-18(25)13-29-31(6,27)28)22(5)14(2)8-10-23(15(3)20(21)26)11-9-16(24)19(22)23/h7,14-15,17,19-20,26H,1,8-13H2,2-6H3/t14-,15+,17-,19+,20+,21-,22+,23+/m1/s1
60924-38-1Relevant articles and documents
ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES
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Page/Page column 27-28, (2021/11/06)
Compounds of formula (1) comprising a pleuromutilin backbone with a triazole based side-group at C22 are provided. The compounds can be used for treatment of bacterial infections and fungal infections. Importantly, infections caused by multidrug-resistant
Synthesis of the pleuromutilin antibiotic SB-268091: A new practical and efficient synthesis of quinuclidine-4-thiol
Choudary, Bernie,Giles, Robert G.,Jovic, Florence,Lewis, Norman,Moore, Steve,Urquhart, Michael
, p. 1927 - 1939 (2013/03/13)
A synthesis of the pleuromutilin antibiotic SB-268091 is described which includes a new and improved route to the quinuclidine-4-thiol ligand. This chemistry has been run on multikilo scale and involved a reductive double debenzylation using sodium in liquid ammonia. Alternative conditions have been developed to prepare quinuclidine-4-thiol which avoid the use of sodium in liquid ammonia. The generality of this process to prepare differentially S-protected quinuclidine-4-thiols is also discussed and exemplified by the preparation of a range of analogues.
Process for the preparation of Retapamulin and its intermediates
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Page/Page column 3; 4, (2009/06/27)
Processes for preparing tropine derivatives of the following Formula B are provided where LG represents a leaving group. The tropine derivatives may be used to prepare Retapamulin, preferably in substantially pure form. Also provided are processes for preparing Retapamulin comprising combining a base, tropine thiol in a free base or salt form, an organic solvent, and a pleuromutilin derivative of Formula A: