60947-52-6

Basic information

• Product Name: (1,4-dinitro-3-phenyl-butan-2-yl)benzene
• CAS NO: 60947-52-6
• Molecular Formula: C₁₆H₁₆N₂O₄
• Molecular Weight: 300.314
• Mol File: 60947-52-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 440.6°Cat760mmHg
• Flash Point: 201.2°C
• Density: 1.235g/cm³
• CAS DataBase Reference: (1,4-dinitro-3-phenyl-butan-2-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (1,4-dinitro-3-phenyl-butan-2-yl)benzene(60947-52-6)
• EPA Substance Registry System: (1,4-dinitro-3-phenyl-butan-2-yl)benzene(60947-52-6)

Safety Data

• Hazardous Substances Data: 60947-52-6(Hazardous Substances Data)

Usage

Description

(1,4-dinitro-3-phenyl-butan-2-yl)benzene, commonly referred to as DNPB, is a yellow crystalline solid that is a member of the nitroaromatic compounds family. It is characterized by its insolubility in water and is recognized for its applications in various industrial sectors.

Uses

Used in Dye and Pigment Production:
DNPB is utilized as a key intermediate in the synthesis of dyes and pigments, contributing to the vibrant coloration and stability of these products in various applications.
Used in Pharmaceutical Manufacturing:
In the pharmaceutical industry, DNPB serves as a crucial component in the production of certain medications, highlighting its importance in the development of healthcare solutions.
Used in Organic Synthesis:
DNPB is employed as a versatile chemical intermediate in organic synthesis, enabling the creation of a wide range of organic compounds for diverse applications.
Used in Chemical Intermediates:
As a chemical intermediate, DNPB plays a significant role in the synthesis of other complex chemical compounds, facilitating advancements in the chemical industry.

Upstream product

• 5153-67-3 nitrostyrene 
• 102-96-5 (2-nitroethenyl)benzene 
• 103-63-9 1-phenyl-2-bromoethane 
• 60-29-7 diethyl ether 
• 64-19-7 acetic acid 
• 7647-01-0 hydrogenchloride 
• 75-52-5 nitromethane 
• 134-81-6 benzil 
• 6125-24-2 2-Phenylnitroethane 

Relevant articles and documents

Cathodic hydrodimerization of nitroolefins

Nitroalkenes are easily accessible in high variety by condensation of aldehydes with aliphatic nitroalkanes. They belong to the group of activated alkenes that can be hydrodimerized by cathodic reduction. There are many olefins with different electron withdrawing groups used for cathodic hydrodimerization, but not much is known about the behaviour of the nitro group. Synthetic applications of this group could profit from the easy access to nitroolefins in large variety, the C-C bond formation with the introduction of two nitro groups in a 1,4-distance and the conversions of the nitro group by reduction to oximes and amines, the conversion into aldehydes and ketones via the Nef reaction and base catalyzed condensations at the acidic CH bond. Eight 1-aryl-2-nitro-1-propenes have been electrolyzed in an undivided electrolysis cell to afford 2,5-dinitro-3,4-diaryl hexanes in high yield. The 4-methoxy-, 4-trifluoromethyl-, 2-chloro- and 2,6-difluorophenyl group and furthermore the 2-furyl and 2-pyrrolyl group have been applied. The reaction is chemoselective as only the double bond but not the nitro group undergoes reaction, is regioselective as a β,β-coupling with regard to the nitro group and forms preferentially two out of six possible diastereomers as major products.

Instantaneous SmI2/H2O/amine mediated reduction of nitroalkanes and α,β-unsaturated nitroalkenes

A rapid method for efficient reduction of nitroalkanes and α,β-unsaturated nitroalkenes using SmI2/H2O/amine has been developed.

Titanium(III) Chloride Mediated Reduction of 1-Nitro-2-phenylethenes

The reaction of 1-nitro-2-phenylethenes (β-nitrostyrenes) with aqueous titanium(III) chloride afforded substituted pyrroles in addition to the expected reduction products, oximes and carbonyl compounds. 2-Substituted 1-nitro-2-phenylethenes yielded divinylamine derivatives instead of pyrroles.The reaction mechanism has been rationalized by taking account of the electron transfer from titanium(III) species to the nitro olefines, followed by protonation, dimerization, cyclization, and/or hydrolysis.