6096-83-9

Basic information

• Product Name: 2-BROMO-1-(3-BROMO-4-METHOXYPHENYL)ETHANONE
• Synonyms: 2-BROMO-1-(3-BROMO-4-METHOXYPHENYL)ETHANONE;2,3'-DIBROMO-4'-METHOXYACETOPHENONE;ACETOPHENONE, 2,3'-DIBROMO-4'-METHOXY-;BROMOMETHYL 3-BROMO-4-METHOXYPHENYL KETONE;UKRORGSYN-BB BBV-2087994;2-Bromo-3'-bromo-4'-methoxyacetophenone
• CAS NO: 6096-83-9
• Molecular Formula: C₉H₈Br₂O₂
• Molecular Weight: 307.97
• Mol File: 6096-83-9.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-BROMO-1-(3-BROMO-4-METHOXYPHENYL)ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-1-(3-BROMO-4-METHOXYPHENYL)ETHANONE(6096-83-9)
• EPA Substance Registry System: 2-BROMO-1-(3-BROMO-4-METHOXYPHENYL)ETHANONE(6096-83-9)

Safety Data

• Hazardous Substances Data: 6096-83-9(Hazardous Substances Data)

Usage

General Description

2-Bromo-1-(3-bromo-4-methoxyphenyl)ethanone is a chemical compound with the chemical formula C9H8Br2O2. It is a white to off-white crystalline solid that is used in various industrial applications. 2-BROMO-1-(3-BROMO-4-METHOXYPHENYL)ETHANONE is a brominated derivative of ethanone and contains both bromine and methoxy groups attached to a phenyl ring. It is commonly used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Additionally, it is also used as a reagent in organic chemistry reactions, particularly in the formation of carbon-carbon bonds. Due to its reactivity and potential health hazards, proper safety precautions should be taken when handling and using this chemical.

Upstream product

• 35310-75-9 3-bromo-4-methoxyacetophenone 
• 50870-41-2 4,4,8,8-Tetrabrom-1,5-dimethoxy-tricyclo-<5.1.0.0.3.5>-octan 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 637-69-4 4-Methoxystyrene 
• 3114-30-5 1-(3,4-dibromophenyl)ethan-1-one 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 

Downstream Products

• 6285-62-7 2-(3-bromo-4-methoxy-phenyl)-indolizine 
• 109016-34-4 2-(3-bromo-4-methoxy-phenyl)-imidazo[1,2-a]pyrimidine 
• 100873-98-1 2-(3-bromo-4-methoxy-phenyl)-6-chloro-imidazo[1,2-a]pyridine 
• 6411-00-3 {[2-(3-Bromo-4-methoxy-phenyl)-2-oxo-ethyl]-methoxycarbonylmethyl-amino}-acetic acid methyl ester 
• 23722-38-5 ω-Hydrazono-3-brom-4-methoxy-acetophenon 
• 76006-37-6 1-(3-bromo-4-methoxy-phenacyl)-pyridinium; bromide 
• 171888-44-1 5-(3-bromo-4-methoxyphenyl)-6-[4-(methylsulfonyl)phenyl]spiro[2.4]hept-5-ene 
• 1026492-85-2 [3-(3-Bromo-4-methoxy-phenyl)-1-hydroxymethyl-4-(4-methanesulfonyl-phenyl)-cyclopent-3-enyl]-methanol 
• 1027533-14-7 3-(3-Bromo-4-methoxy-phenyl)-4-(4-methanesulfonyl-phenyl)-cyclopent-3-ene-1,1-dicarboxylic acid dimethyl ester 
• 1027988-15-3 C₃₅H₃₅BrO₉S₃ 
• 5502-59-0 {[2-(3-Bromo-4-methoxy-phenyl)-2-oxo-ethyl]-carboxymethyl-amino}-acetic acid 
• 1196105-19-7 2-(3-bromo-4-methoxyphenyl)quinoxaline 
• 1156766-40-3 1-(3-bromo-4-methoxyphenyl)-2-(3-methoxyphenylthio)ethanone 
• 1649501-82-5 (3-bromo-4-methoxyphenyl)(6-methoxybenzo[b]thiophen-2-yl)methanone 

Relevant articles and documents

Synthesis and pharmacological evaluation of naftopidil-based arylpiperazine derivatives containing the bromophenol moiety

Background: Prostate cancer (PCa) is the most common malignancy in men and in the absence of any effective treatments available. Methods: For the development of potential anticancer agents, 24 kinds of naftopidil-based arylpiperazine derivatives containin

Synthesis method for aromatic ring bromination of acetophenones derivative

The invention relates to a synthesis method for aromatic ring bromination of an acetophenones derivative, and belongs to the technical field of organic synthesis. The synthesis method consists of twokinds of synthesis methods: method A, adding the acetophenone derivative into a first oxidizing agent and stirring to form a suspension system, controlling the temperature of the suspension system tobe 10-50 DEG C, adding a first reducing agent or a second reducing agent, stirring and reacting for 2-20 h, and performing aftertreatment after the reaction is completed to obtain the aromatic ring brominated acetophenone derivative; method B, adding the acetophenone derivative into the second reducing agent and stirring to form a suspension system, controlling the temperature of the suspension system to be 10-50 DEG C, then adding a second oxidizing agent or the first oxidizing agent, stirring and reacting for 2-20 h, and performing aftertreatment after the reaction is completed to obtain thearomatic ring brominated acetophenone derivative. According to the synthesis method provided by the invention, an inorganic and non-toxic bromination reagent is used, water is used as a reaction solvent, the prepared product is mutually incompatible with water, so that separation and the aftertreatment are convenient to perform, therefore, the synthesis method of the invention is applicable to large-scale industrial production of intermediate products for aromatic ring bromination of the acetophenones derivative.

1,3-Dibromo-5,5-dimethylhydantoin mediated oxidative amidation of terminal alkenes in water

A variety of terminal alkenes were converted to the corresponding amides in yields of 25 to 86% in water via treatment with 1,3-dibromo-5,5-dimethylhydantoin, followed by reaction with molecular iodine and aq. NH3 (or amine) in one pot. This metal- and organic solvent-free protocol is not only suitable for styrene derivatives, but also, for the first time, works well on terminal aliphatic alkenes.