61-56-3 Usage
Chemical Properties
Off-White Solid
Uses
Different sources of media describe the Uses of 61-56-3 differently. You can refer to the following data:
1. Sultiame is a benzenesulfonamide derivative. Sultiame acts as an inhibitor of the enzyme carbonic anhydrase. Sulthiame is used as an anticonvulsant in the treatment of benign and symptomatic focal epilepsy.
2. Sulthiame is a benzenesulfonamide derivative. Sulthiame acts as an inhibitor of the enzyme carbonic anhydrase. Sulthiame is used as an anticonvulsant in the treatment of benign and symptomatic focal epilepsy.
Brand name
Conadil (3M Pharmaceuticals); Trolone (3M Pharmaceuticals).
Check Digit Verification of cas no
The CAS Registry Mumber 61-56-3 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 6 and 1 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 61-56:
(4*6)+(3*1)+(2*5)+(1*6)=43
43 % 10 = 3
So 61-56-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2O4S2/c11-18(15,16)10-5-3-9(4-6-10)12-7-1-2-8-17(12,13)14/h3-6H,1-2,7-8H2,(H2,11,15,16)
61-56-3Relevant articles and documents
Enantioselective Hydroamination of Alkenes with Sulfonamides Enabled by Proton-Coupled Electron Transfer
Demaerel, Joachim,Graff, David E.,Knowles, Robert R.,Roos, Casey B.
supporting information, p. 5974 - 5979 (2020/04/27)
An enantioselective, radical-based method for the intramolecular hydroamination of alkenes with sulfonamides is reported. These reactions are proposed to proceed via N-centered radicals formed by proton-coupled electron transfer (PCET) activation of sulfonamide N-H bonds. Noncovalent interactions between the neutral sulfonamidyl radical and a chiral phosphoric acid generated in the PCET event are hypothesized to serve as the basis for asymmetric induction in a subsequent C-N bond forming step, achieving selectivities of up to 98:2 er. These results offer further support for the ability of noncovalent interactions to enforce stereoselectivity in reactions of transient and highly reactive open-shell intermediates.
